Lesson 2.2 P2

Question 1

immune related diseases

Answer 1

Primary sclerosis cholangitis

secondary sclerosis cholangitis

Question 2

what is primary sclerosis cholangitis

Answer 2

chronic inflammatory disease of entire biliary tree

Question 3

what is seen with primary sclerosis cholangitis

Answer 3

fibrosing inflammation of small and large bile ducts

Question 4

primary sclerosis cholangitis is more common in men or women

Answer 4

men

Question 5

age for primary sclerosis cholangitis

Answer 5

39 years

Question 6

primary sclerosis cholangitis, 80% of patients have

Answer 6

inflammatory bowel disease

Question 7

primary sclerosis cholangitis leads to (5)

Answer 7

biliary strictures
cholestasis
biliary cirrhosis
portal hypertension 
hepatic failure

Question 8

secondary sclerosis cholangitis ethology

Answer 8

AIDS cholangiopathy 
Bile duct neuroplasm 
biliary tract surgery 
trauma 
choledocholithiasis 
congenital anomalies 
ischemic structuring of bile ducts 
toxic strictures
primary sclerosis cholangitis

Question 9

Biliary tree neoplasms

Answer 9

cholangiocarcinoma
hilar/ klatskins tumor
Distal (CBD) cholangiocarcinoma
intrahepatic/ intraductural cholangiocarcinoma

Question 10

what is cholangiocarcinoma

Answer 10

a cancerous growth in one of the ducts that carries bile from the liver to the small intestine

Question 11

3 risk factors of cholangiocarcinoma

Answer 11

age, recurrent biliary infections, stone disease

Question 12

90% of cholangiocarcinoma are

Answer 12

adenocarcinoma

Question 13

3 classifications of cholangiocarcinoma and their %

Answer 13

hilar - 60% - klatskins tumor
Distal - 30% distal CBD
Intrahepatic - 10% aka peripheral

Question 14

where is klatskins tumour located

Answer 14

in porta hépatis

Question 15

what does klatskins tumour cause

Answer 15

fibrous tissue formation

Question 16

symptoms of klatskins tumour

Answer 16

jaundice, pruritus, increased LFTs, nodes

Question 17

What is seen commonly with Distal (CBD) cholangiocarcinoma

Answer 17

polypoid masses

progressive jaundice

Question 18

what is most effective treatment of Distal (CBD) cholangiocarcinoma

Answer 18

surgical resection

Question 19

where do Distal (CBD) cholangiocarcinoma tumors extend into

Answer 19

distal CBD

Question 20

intrahepatic cholangiocarcinoma is

Answer 20

2nd most common primary malignancy of the liver

Question 21

intrahepatic cholangiocarcinoma due to

Answer 21

liver cirrhosis and Hep C

Question 22

intrahepatic cholangiocarcinoma appears as _______ on US

Answer 22

large solid hypovascular mass with varying degree of echogenicity

Question 23

intrahepatic cholangiocarcinoma differentiated from HCC by

Answer 23

presence of Ductal obstruction

Question 24

intrahepatic cholangiocarcinoma is hard to differentiate from

Answer 24

mets

Question 25

what are common sites of metastases to biliary tree (3)

Answer 25

breast, colon and melanoma

Question 26

What Is the HIDA scan for

Answer 26

most often done to evaluate the GB and bile excretion function of liver

tests rate at which bile is being released from GB

Question 27

HIDA can help diagnose (5)

Answer 27

GB inflammation
bile duct obstruction 
congenital abnormalities in the bile ducts
post op complications 
assessment of liver transplant