Lesson 2.2 P2 Flashcards
immune related diseases
Primary sclerosis cholangitis
secondary sclerosis cholangitis
what is primary sclerosis cholangitis
chronic inflammatory disease of entire biliary tree
what is seen with primary sclerosis cholangitis
fibrosing inflammation of small and large bile ducts
primary sclerosis cholangitis is more common in men or women
men
age for primary sclerosis cholangitis
39 years
primary sclerosis cholangitis, 80% of patients have
inflammatory bowel disease
primary sclerosis cholangitis leads to (5)
biliary strictures cholestasis biliary cirrhosis portal hypertension hepatic failure
secondary sclerosis cholangitis ethology
AIDS cholangiopathy Bile duct neuroplasm biliary tract surgery trauma choledocholithiasis congenital anomalies ischemic structuring of bile ducts toxic strictures primary sclerosis cholangitis
Biliary tree neoplasms
cholangiocarcinoma
hilar/ klatskins tumor
Distal (CBD) cholangiocarcinoma
intrahepatic/ intraductural cholangiocarcinoma
what is cholangiocarcinoma
a cancerous growth in one of the ducts that carries bile from the liver to the small intestine
3 risk factors of cholangiocarcinoma
age, recurrent biliary infections, stone disease
90% of cholangiocarcinoma are
adenocarcinoma
3 classifications of cholangiocarcinoma and their %
hilar - 60% - klatskins tumor
Distal - 30% distal CBD
Intrahepatic - 10% aka peripheral
where is klatskins tumour located
in porta hépatis
what does klatskins tumour cause
fibrous tissue formation
symptoms of klatskins tumour
jaundice, pruritus, increased LFTs, nodes
What is seen commonly with Distal (CBD) cholangiocarcinoma
polypoid masses
progressive jaundice
what is most effective treatment of Distal (CBD) cholangiocarcinoma
surgical resection
where do Distal (CBD) cholangiocarcinoma tumors extend into
distal CBD
intrahepatic cholangiocarcinoma is
2nd most common primary malignancy of the liver
intrahepatic cholangiocarcinoma due to
liver cirrhosis and Hep C
intrahepatic cholangiocarcinoma appears as _______ on US
large solid hypovascular mass with varying degree of echogenicity
intrahepatic cholangiocarcinoma differentiated from HCC by
presence of Ductal obstruction
intrahepatic cholangiocarcinoma is hard to differentiate from
mets
what are common sites of metastases to biliary tree (3)
breast, colon and melanoma
What Is the HIDA scan for
most often done to evaluate the GB and bile excretion function of liver
tests rate at which bile is being released from GB
HIDA can help diagnose (5)
GB inflammation bile duct obstruction congenital abnormalities in the bile ducts post op complications assessment of liver transplant
