Lecture4 Flashcards

1
Q

what is saturation

A

absolute refractory period…no APs can be fired

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2
Q

3 ways of representing information

A

place coding
frequency coding
recruitment

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3
Q

space between saturation and threshold is known as

A

dynamic range

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4
Q

what does dc/ml respond to

A

touch
vibration
proprioception

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5
Q

what does anterolateral respond to

A

pain and temperature

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6
Q

axons that terminate in the VPL thalamus have cell bodies in the _____ nuclei

A

cuneate or gracile

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7
Q

axons for DC/ML system are coming from

A

body and poster 1/3 of head

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8
Q

mechanoreceptors for lower part of body are in the ___ spinal cord

A

lumbar

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9
Q

mechanoreceptors for upper part of body are in the ___ spinal cord

A

cervical

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10
Q

DC/ML
1st order
2nd order
3rd order

A

1: DRG
2: cuneate or gracile nuclei
3: VPL

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11
Q

Trigeminal
1st order
2nd order
3rd order

A

1: trigemina ganglion
2: ipsilateral principal trigeminal nucleus
3: VPM

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12
Q

Ad fibers main projection?

A
marginal zone (laminae 1)
also some laminae 5 projections
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13
Q

C fibers main projection

A

substantia gelatinosa (laminae 2)
also some laminae 1 projection
will go to thalamus, midbrain, or reticular formation

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14
Q

cell bodies of Ad fibers are in?

A

DRG

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15
Q

cell bodies of C fibers are in?

A

DRG

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16
Q

laminae 1 nuerons form which pathway?

A

neospinothalamic

17
Q

when does windup happen

A

in response to activation of tonic receptors of nociceptive afferents

18
Q

why does windup happen

A

response won’t outlast stimulus BUT will fire rapidly to get a stronger signal (so you can feel the stimulus and stop it if it causing you pain)

19
Q

where does primary hyperalgesia occur

A

tissues

20
Q

where does secondary hyperalgesia occur

A

spinal cord

21
Q

VPL is sensory for the

A

body

22
Q

VPM is sensory for the

A

face

23
Q

fn of intralaminar nuclei

A

alterness
arousal
pain

24
Q

VPL gets input form

A

body and 1/3 of face

25
Q

VPM gets input from

A

trigeminal system

26
Q

VP thalamus projects to

A

SI- primary somatic somatosensory cortex

27
Q

where is the first site for bilateral input

A

SII- secondary somatic somatosensory cortex

28
Q

SII projects to

A

limbic system (amygdala and hippocampus): learning + memory
motor cortex
auditory and visual association areas
back to SI

29
Q

Types of receptors in the major sensory systems

A

mechanoreceptors
nociceptors and thermoreceptors
proprioceptors

30
Q

which receptors have free nerve endings

A

nociceptors

thermoreceptors

31
Q

which receptors have encapsulated nerve endings

A

mechanoreceptors

  1. messiness corpuscles
  2. merkles disk
  3. pacinian corpuscles
  4. ruffian endings
32
Q

fn of meissners corpuscles

A

respond well to light touch and light movement of skin

33
Q

fn of merkels disk

A

respond well to touch and pressure

34
Q

fn of pacinian corpuscles

A

respond well to vibrations

35
Q

fn of ruffian endings

A

respond well to stretching of muscles

36
Q

three types of proprioceptive mechanoreceptors

A

muscle spindles
golgi tendon organs
joint receptors

37
Q

fn of muscle spindles

A

respond well to stretch, length, and rate of change

38
Q

fn of GTO

A

in tendons, respond well to force of muscle length

39
Q

two types of adaptation

A

phasic

tonic