Lecture 00 Flashcards
What are the two types of brain cells?
1) Neurons
2) Glia
What are the types of glia?
1) astrocytes
2) oligodendrocytes + Schwann cells
3) microglia
What is the job of a dendrite? (what system is it receiving information from and where does it send it?)
to receive a signal/information from PNS to CNS
what is the job of an axon? (what system is it receiving information from and where does it send it?)
to send a signal/information from CNS to PNS
synaptic ends are also called?
boutons
why does the brain use so much ATP
uses ATP to keep cells at RMP ( 1 ATP is used in every cell for the 3 Na + - 2 K + exchange)
Classifications of neurons are based on?
1) number of neuritis in the body
2) connections
3) dendrites
4) axon length
5) neurotransmitters
types of neurites found in the body
unipolar ex. dorsal root ganglion
bipolar ex. retina
multipolar ex. motor neurons
what type of connections are found between neurons
primary sensory: afferent
motor neurons: efferent
internuerons
remember: ME for motor neurons, then PSA for primary sensory
what types of dendrites
pyramidal v. stellate
spiny v. aspinous
whats so special about spines on dendrites
these spines are small input sites. these sites are where you get changes with learning.
Projection neurons are what type of cells of the cortex?
pyramidal cells
local circuit neurons are what type of cells of the cortex
stellate cells
What role do MAPs play?
microtubule associated proteins are proteins that hold mircotubules together
MAPs and alzheimers?
the proteins become unhinged and accumulate in cell bodies and neurofibulary tangles
Where is the axon hillock located
located right after cell body, very beginning of axon
what happens at the axon hillock?
action potential starts
Which direction does anterograde axonal transport go?
cell body to terminal
which direction does retrograde axonal transport go
terminal to cell body
why is retrograde axonal transport important
send information from axon back to cell
BUT
toxins can also travel to brain i.e. tetanus
ALSO
can use it in scientific experiments to figure out pathway of axons
Functions of astrocytes
- mop up excess K+, prevent cells from depolarizing
- help developing cells migrate to the right areas of the brain
- create scar tissue if theres a brain injury *
- astrocytic feet attach to blood brain barrier capillaries
- if there is too much scar tissue, cancerous tumors can form, astrocytic tumors begin the most common
Oligodendrocytes and Schawan cells make what? and where?
Oligo + Schwann –> myelin sheath
oligo: CNS
Schwann: PNS
Functions of microglia
act as macrophages, clean up waste
i.e. if you have an injury, macroglia become macrophages and clean up da mess