Lecture 10 Flashcards
5 nuclei of BG…go!
Telencephalon
- caudate
- putamen
- GPe/GPi
Diencephalon
4. subthalamnic nucelus
Midbrain
5. substania nigra
output of cerebellum…excitatory or inhibitory?
excitatory
output of BG…excitatory or inhibitory?
inhibitory
striatum =
caudate + putamen
what NT in what nucleus in responsible for parkinson
dopamine
substania niga pars compacta
GPe is major (a) for (b)
and inhibitory for (c)
a) input
b) subthalamic nucleus
c) subthalamic nucleus
GPi is major (a) for (b) and in (c) for cortex and thalamus
a) output
b) BG
c) inhibitory for cortex and thalamus
what modulates output of striatum
substania nigra
what modulates output of GPe/GPi
subthalamic nucleus
direct pathway of BG Fn
activate thalamus + initiate movement
indirect pathway of BG Fn
inhibit movements
draw pathways of BG
-
FN of flocconodular lobe
receiving input from vestibular system so, maintenance of balance
FN of ant lobe
control limb movments while movements are being exectued
FN of post lobe
learn skilled movements and stores that information
flocconodular lobe AKA?
vestibulocerebellum
ant lobe AKA
spinocerebellar
post lobe AKA
cerebrocerebellar
output nuclei fo flocconodular lobe
fastigial nucleus
output nuclei of ant lobe
interposed ( globose + emboliform)
output nuclei of post lobe
dentate nucleus
3 loops in BG
motor loop
limbic loop
executive loop
Fn of motor loop
selection + initiation of movement
fn of limbic loop
regulation of cognitive processes i.e. attention
fn of executive loop
regulation of emotion
what tracts used for lower limbs in ant lobe
dorsal and ventral spinocerbellar
what tracts used for upper limbs in ant lobe
cuneocerebellar and rostral spinocerebellar
what tracts are used for feedback for exectution movements
DSCT
cuneocerebellar
what tracts used for intention of movements
VSCT
RSCT
which nuclei does anterior lobe (spinocerebellar tract) use?
project to?
interpose nuclei
project to: red nucleus + RST
mossy fibers have axons from
pontine nuclei
spinocerebellar
vestibulo-cerebellar
mossy fibers are excitatory to (a) cells
using (b) NT
(a) granule
(b) glutamate
climbing fibers are excitatory to (a) cells using (b) NT
(a) pukinje
(b) aspartate
climbing fibers get info from
inferior olive
intended movement uses whihc cerebellar input
cortico-ponto
actual movement uses which cerebellar input
cuneo
dorsal
vestibular
mesocortical- cognitive fn or emotional?
cognitive
mesolimbic- cognitive fn or emotional?
emotional
