Lecture 9 - Threonine/Glycine/Serine Example Flashcards

1
Q

Step 1a

A

Threonine -> acetaldehyde

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2
Q

Step 2a

A

Acetaldehyde -> acetate

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3
Q

Step 3a

A

Acetate -> acetyl CoA

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4
Q

Step 2b

A

Glycine -> serine

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5
Q

Step 3b

A

Serine -> pyruvate

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6
Q

Step 4b

A

Pyruvate -> acetyl CoA

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7
Q

Step 1b

A

Threonine -> glycine

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8
Q

Enzyme of step 1b

A

Serine hydroxymethyl transferase (threonine aldolase)

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9
Q

Cofactor of step 1b

A

None

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10
Q

Enzyme of step 2b

A

Serine hydroxymethyl transferase (threonine aldolase)

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11
Q

Cofactor of step 2b

A

FH4-CH2OH -> FH4

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12
Q

Enzyme of step 3b

A

Serine dehydratase

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13
Q

Cofactor of step 3b

A

NH3 out

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14
Q

Enzyme of step 4b

A

Pyruvate dehydrogenase

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15
Q

Cofactor of step 4b

A
  • NAD+ -> NADH + H+

- CoASH -> CO2

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16
Q

Enzyme of step 2a

A

Acetaldehyde dehydrogenase

17
Q

Cofactor of step 2a

A

NAD+ + H2O -> NADH + H+

18
Q

Enzyme of step 3a

A

Acetyl CoA synthetase

19
Q

Cofactor of step 3a

A

ATP -> AMP + PPi

20
Q

What enzyme converts AMP + PPi to 2 Pi and what is the cofactor?

A
  • IPPase

- H2O in

21
Q

What enzyme converts ethanol to acetaldehyde and what is the cofactor?

A
  • Alcohol dehydrogenase

- NAD+ -> NADH + H+