Lecture 14 - Valine Synthesis Mechanism Flashcards by Anna Van Dekerkhove | Brainscape

Q

Which organisms can synthesize valine?

A

Plants, bacteria, and fungi

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Q

_____ inhibit acetolactate synthase

A

Some herbicides

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Q

Step 1

A

Pyruvate -> acetolactate

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Q

Enzyme of step 1

A

Acetolactate synthase

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Q

Cofactor of step 1

A

Pyruvate -> CO2

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Q

Step 2

A

Acetolactate -> dihydroxy isovalerate

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Q

Enzyme of step 2

A

Acetolactate isomeroreducatase

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Q

Cofactor of step 2

A

NADPH + H+ -> NADP+

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Q

Step 3

A

Dihydroxy isovalerate -> alpha-keto isovalerate

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Q

Enzyme of step 3

A

Dihydroxy isovalerate dehydratase

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Q

Cofactor of step 3

A

H2O out

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Q

Step 4

A

Alpha-keto isovalerate -> valine

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Q

Enzyme of step 4

A

Branched chain amino acid transaminase

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Q

Cofactor of step 4

A

Glutamate -> alpha-ketoglutarate

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Q

How many molecules of pyruvate are used to make valine?

A

2

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