Lecture 9 Common Pathologies of Pregnancy

Question 1

Name 4 causes of miscarriages

Answer 1

Foetal Problems
Placenta/membrane/cord problems
Uterus/cervix problems
Maternal health issues

Question 2

Name 2 methods to treat an ectopic pregnancy

Answer 2

Methotrexate

Surgery (salpingectomy)

Question 3

Define a Molar Pregnancy

Answer 3

Caused by 2 sperms fertilising one egg with no chromosomes resulting in an imbalance of methylated genes and trophoblast overgrowth

Question 4

Diabetes in 1st trimester can lead to____

Answer 4

Malformations

Question 5

Diabetes in 3rd trimester can lead to____

Answer 5

Intrauterine death

Question 6

How can diabetes affect the delivery of the baby

Answer 6

Huge babies that obstruct labour

Question 7

What is acute chorioamnionitis

Answer 7

Inflammation in membranes, cord and foetal plate of placenta

Question 8

What is the clinical presentation of acute chorioamnionitis

Answer 8

Mother presents with fever

Raised neutrophils in blood

Question 9

What are the complications of acute chorioamnionitis

Answer 9

Intrauterine death
Cerebral palsy later in life
Cytokine storm that activates some brain cells and is damaged by normal hypoxia of labour

Question 10

What are the causes of placental abruption

Answer 10

Hypertension
Trauma
Cocaine

Question 11

What are the symptoms of placental abruption

Answer 11

Vaginal bleeding
Haematoma
Decrease in baby’s oxygen from mother