Lecture 23 Workshop Clinical Pathological Conference of the Uterus Flashcards
What is type 1 endometrial cancer
Common
Hyperplasia with atypia precursor
What is type 2 endometrial cancer
High grade, more aggressive, worse prognosis
Older women
Stage 1A endometrial cancer
Inner half of myometrium
Stage 1B endometrial cancer
Outer half of mymetrium
Stage 2 endometrial cancer
Invades cervix
Stage 3A endometrial cancer
Serosa/adnexa
Stage 3B endometrial cancer
Vagina/parametrium
Stage 3C endometrial cancer
Pelvic or para-aortic nodes
Stage 4 endometrial cancer
Bladder/bowel/intra-abdominal/inguinal nodes
What is the treatment for early stage endometrial cancer treatment
Surgery TAH/BSO/washings
What is the treatment for high risk histology for endometrial cancer
Chemo
What is the treatment for advanced stage endometrial cancer
Radiotherapy
What is the treatment for palliative care for endometrial cancer
Progesterone
What are risk factors for endometrial cancer
Post-menopausal women
High circulating oestrogen levels (obesity, unopposed E2 therapy/Tamoxifen, PCOS, early menarche/late menopause)
Endometrial hyperplasia with atypia
HNPCC
What are the symptoms of endometrial cancer
Abnormal vaginal bleeding
Post-menopausal bleeding