lecture 6 phamrma of airways

Question 1

leukotrienes cause

Answer 1

bronchoconstriction

Question 2

what reveses bronchoconstriction

Answer 2

adrenalin

Question 3

adrenalin works on

Answer 3

beta adrenergic receptros

Question 4

what happens when adrenalin binds to its receptor

Answer 4

conformation change and change in the G protein

Question 5

salbutamol targets

Answer 5

beta 2 in the lungs

Question 6

what are adrenalin and isoprenalin metabolised by

Answer 6

catacholamine transferase

Question 7

exaples of long acting for asthma

Answer 7

formetarol and salmetrol

Question 8

what recruits eosinophils

Answer 8

leukotrine B4

Question 9

what else are eosinophils good against

Answer 9

worms

Question 10

where are alpha receptors

Answer 10

arteries and veins

Question 11

where is beta 1

Answer 11

heart

Question 12

where is beta 2

Answer 12

lungs

Question 13

what is increased with steroids

Answer 13

beta 2 receptors

apoptosis of eosinophils

Question 14

steroids cause

Answer 14

cushings

Question 15

inhaled steroids can..(bad)

Answer 15

stunt growth

Question 16

long acting beta agonist

Answer 16

symbicort

Question 17

leukotriene antagonist

Answer 17

montelukast

Question 18

cytokines are blocked by

Answer 18

steroids

Question 19

theophylline class

Answer 19

methyxanthine

Question 20

theophylline action

Answer 20

bronchodilator

Question 21

bad about theophylline

Answer 21

makes you puke

Question 22

what blocks IL5

Answer 22

mepolizumab

Question 23

what recruits eosinophils

Answer 23

IL5

Question 24

smoking cessation drug

Answer 24

champix

Question 25

long acting muscarinic agonist

Answer 25

tiotropium

Question 26

what does tiotropium work on

Answer 26

M3 receptors