lecture 10 cardiac consequences of atheroma Flashcards

1
Q

ethnicity predisposed to atheroma

A

south east asians

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2
Q

risk factors you can change

A

smoking, diabetes mellitus, obesity, lipids, hypertension, diet, pollution, stress and exercise

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3
Q

risk factors you cant change

A

family history, gender, age and ethnicity

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4
Q

what forms on the fatty streak of the atheroma

A

fibrous cap

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5
Q

what is at the core of the atheroma

A

lipid core

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6
Q

what does the vessel do at first when there is an atheroma

A

dilates to compensate

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7
Q

what happens when the cap ruptures

A

lipid are exposed to circulation which initiates thrombotic cascade

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8
Q

where may angina radiate

A

arms
jaw
neck and teeth

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9
Q

how is stable angina relieved

A

rest and nitrites

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10
Q

how is stable angina confirmed

A

stress testing

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11
Q

what does the ECG look like for stable angina

A

normal at rest

ST depression on walking

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12
Q

unstable angina pathology

A

myocardial necrosis

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13
Q

symptom of unstable angina

A

random pain

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14
Q

diagnosis of unstable angina

A

troponin

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15
Q

ST elevation cause

A

complete occlusion of a coronary artery

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16
Q

how do you treat complete occlusion of a coronary artery

A

thrombolysis or angioplasty stent implantation

17
Q

isoelectric line

A

flat line on the ECG

18
Q

first sign of a STEMI on ECG

A

slight peak in the T wave

19
Q

what happens after T wave peak in STEMI

A

ST elevation
loss of R wave
big Q wave

20
Q

what supplies the inferior wall

A

right coronary artery

21
Q

left coronary artery divides into

A

LAD and the left circumflex

22
Q

what supples the anterior wall

A

LAD

23
Q

what supplies the lateral wall

A

left circumflex

24
Q

what coronary dominance do most people have

A

right

25
Q

MI of right coronary artery ECG

A

inferior ST elevation MI

26
Q

MI of the LAD ECG

A

anterior ST elevation

27
Q

MI of the circumflex

A

lateral ST elevation

28
Q

things to bear in mine after an MI

A

troponin falls during the following week - not another MI

29
Q

what is troponin

A

protein

30
Q

what is troponin attatched to

A

tropomyosin

31
Q

what binds to the troponin

A

calcium

32
Q

other causes of elevated troponin

A

PE, pulmonary hypertension, septicaemia

33
Q

MI treatment

A

antiplatelets, heparin, statin and anti ischemics

STENTs

34
Q

examples of antiplatelets

A

aspirin

clopidogrel

35
Q

anti ischemic medications

A

vasodilators

such as beta blockers and nitrates

36
Q

what happens between the healthy and necrotic tissue

A

there is rupture = death

PEA

37
Q

how will you see left ventricular dysfunction

A

enlarged heart shadow on radiograph

38
Q

where do the leads of a defib go

A

through the subclavian vein

apex LV and right atrium