Lecture 6- Lymphocytes

Question 1

What is the role of T cells

Answer 1

Regulate adaptive immunity
Cell-mediated immune response
Destroy viral infected cells and tumors

Question 2

What is the role of B cells

Answer 2

Antibody production
Destroy extracellular bacteria and toxins

Question 3

What is the precursor of B and T cells

Answer 3

Bone marrow

Question 4

What is a CD

Answer 4

Cluster of differentiation. Just proteins that identify a lymphocyte, like IgA

Question 5

What properties does Forward Scattered light determine

Answer 5

Cell size

Question 6

What properties does Side-scattered light determine

Answer 6

Interior cell contents

Question 7

Two unique CD on horse lymphocytes

Answer 7

EqWC1 and EqWC2

Question 8

Unique cow CD

Answer 8

BoWC1 - BoWC15

Question 9

Pig unique CD

Answer 9

SWC1- SWC9

Question 10

What is a TCR

Answer 10

T cell receptor

Question 11

What is a BCR

Answer 11

B cell receptor

Question 12

What is the most importatn bacterial antigen

Answer 12

Toxins

Question 13

What is an antigen

Answer 13

A molecule that triggers adaptive immune response

Question 14

What qualities make an antigen more immunogenic

Answer 14

Large size, complex, foreign and stable in the environment

Question 15

Where do immune cells bind on an antigen

Answer 15

The epitope

Question 16

Immunogens vs haptens

Answer 16

Immunogens are complete antigens, haptens are incomplete antigens

Question 17

Positive T cell selection

Answer 17

Thymus presents antigens for immature T cells’ TCR to bind to

Question 18

Negative T cell selection

Answer 18

Thymus presents self antigens to eliminate T cells that bind

Question 19

What couples with haptens to make immunogens

Answer 19

serum or tissue