Lecture 3- Dendritic Cells and Complement

Question 1

What do dendritic cells do when they encounter a pathogen

Answer 1

Ingest using cytoplasmic projections, then display fragments (antigens)

Question 2

What cells do dendritic cells activate

Answer 2

Helper T cells

Question 3

What is the only antigen-presenting cell that can activate a naive T cell?

Answer 3

Dendritic cells

Question 4

Specialized dendritic cells that live in the skin

Answer 4

Langerhans cells

Question 5

Specialized cytoplasmic granules found in Langerhans cells

Answer 5

Birbeck granules

Question 6

Which Dendritic cell types secrete interferon to fight VIRUSES

Answer 6

Plasmacytoid DC and Classical DC1

Question 7

Which Dendritic cell types fight BACTERIAL infections by activating Helper T cells and presenting antigens

Answer 7

Classical DC2 and Follicular DC

Question 8

Where can Complements be made

Answer 8

Liver, macrophages, mast cells, and neutrophils

Question 9

What triggers the innate pathway

Answer 9

mannose-binding lectin binds to a microbe

Question 10

Which pathway involves the formation of the terminal complement complex

Answer 10

Innate pathway

Question 11

What triggers the alternate pathway

Answer 11

C3b protein binds to a microbe

Question 12

What triggers the classical pathway

Answer 12

Antibodies secreted by B cells

Question 13

which two pathways involve C9 polymerization

Answer 13

Innate and alternate

Question 14

Which complement is produced by macrophages

Answer 14

C2

Question 15

Which complement is produced by mast cells

Answer 15

C1q

Question 16

Which complements are produced in neutrophils

Answer 16

C6 and C7

Question 17

Three pathways of complement activation

Answer 17

Innate, alternate, and classical

Question 18

Where do dendritic cells extend to monitor the gut lumen

Answer 18

Lamina propria