LECTURE 5 Flashcards
What are three ways for molecules to move across the membrane
1) diffusion (active transport)
2) facilitated diffusion
3) active transport
Diffusion (active transport)
Occurs best with small hydrophobic molecules (O2), which are soluble in the bilayer.
(Active transport) When a molecule is more once treated on one side of a membrane
Diffusion occurs until equilibrium is reached
Which molecules are from best to warts at diffusing across the membrane in active transport
Hydrophobic = BEST
Small uncharged polar = POOR
Large uncharged polar - RARE
Charges (small or large) = NEVER
Osmosis
Diffusion of water, but solute (sugar) cannot pass.
During osmosis, where dos water move from
Water moves from a place of Low solute concentration to higher clout ion concentration
Tonicity
The relative contraction of a solute in two solution separated by age range that it cannot pass.
- hypotonic
- isotonic
- hypertonic
Hypotonic (less solute)
ANIMAL: influx of water causes osmotic lysis (Lysed). Water going in
PLANT: turger pressure, turgid (normal)
Isotonic
ANIMAL: normal (water going in and out)
PLANT: flaccid (water going in and out)
Hypertonic (more solute)
ANIMAL: shriveled (water going out)
PLANT: plasmolyzed, cell shrinks, membrane pulls always from cell wall = plasmolysis
Types of diffusion or active transport
- osmosis
- tonicity
Facilitated diffusion
Passive transport aided by proteins (transport proteins)
Two types of transport proteins
- channel proteins
- carrier proteins
Channel proteins
A specific channel protein per one type of molecule, cell conditions determine whether closed or open
Two examples of channel proteins
Aquaporins: facilitates osmosis
Ion channel: allows specific ions
Carrier proteins
- undergo change in shape to trans locate a solute across a membrane.
- specific molecule transported down its concentration gradient.
Active transport
Used to move a substance against the concentration gradient
Active transport requires energy, which kind?
ATP
Why do cells do active transport
- to concentrate nutrients in the cell
- to expel waste
- establish (chemical/voltage) gradients
What kinds of proteins are involved in active transport
Carrier proteins, each septic to one substance
Animal cells Martin a high concentration of ____ and a low concetration of _____
High concentration of K+ and a low concentration of Na+
How do cells maintain Na and K levels, and what kind of energy does it use?
Sodium-potassium pump, uses ATP
ATP
Adenosine triphosphate, breaks down ADP +Pi and released energy
ADP
Adenosine diphosphate
Pi
Phosphate
Active trap org allows cells to establish and maintain
Concentration gradients
What are the steps (6) to the sodium-potassium pump?
1) cytoplasmic Na+ binds to the sodium-potassium pump.
2) Na+ blinding stimulates phosphorylation by ATP.
3) phosphorylation causes the protein to change its shape. Na+ expelled
4) K+ bonds and triggers release of phosphate groups
5) loss of phosphate restore proteins original shape
6) K+ released, cycle repeated
Because there are 3 Na going out for every 2 K going in, what does this cause
An imbalance in charge across the membrane, (more negative inside), causing ions to move
Membrane potential
The unique distribution of anions and cations across the plasma membrane.
Tow forces drive the diffusion of ions across the membrane
- a difference in concentration (chemical force)
- a different in charge (electrical force)