Lecture 4 Flashcards

1
Q

What is a lipid composed of? (4•)

A

•Two fatty acid tails
•Glycerol backbone
•Phosphate
•Choline

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2
Q

Lipids with bulky heads and a single hydrophobic fatty acid in a wedge shape form?

A

Spherical structures called micelles.

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3
Q

What type of interactions do fatty acids form with each other?

A

Van der waals forces.

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4
Q

Longer fatty acid tails implies?

A

More area that can have van der waals interactions and the phospholipids can be more mobile.

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5
Q

Double bonding in fatty acids introduce? (2•)

A

•Bents in the fatty acid tails which •reduce tightness and enhance lipid mobility.

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6
Q

What is the main role of cholesterol?

A

It controls the fluidity of the membrane depending on temperature.

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7
Q

Integral membrane proteins?

A

Permanently associated with the cell membrane and cannot be separated without destroying the membrane.

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8
Q

How does the cell remain homeostasis?

A

By being semipermeable.

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9
Q

Semipermeability?

A

It means that the cell selects what goes in or out.

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10
Q

How does permeability work?

A

•The hydrophobic interior of the lipid belayer prevents ions and charged polar molecules from moving across it.
•Small non-polar molecules and gasses (sometimes small uncharged polar molecules such as water) can freely move across the membrane.
•Protein channels and transporters can move ions, water, and nutrients that cannot cross the membrane alone.

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11
Q

Passive transport?

A

It works by diffusion which is the net movement of molecules through the membrane depending on the concentration gradient. However, there are a few exceptions for this concentration phenomenon, like oxygen and carbon dioxide.

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12
Q

Does the movement of molecules stop if there is no concentration gradient?

A

No, molecules still freely move.

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13
Q

Facilitated diffusion?

A

When a molecule that requires a protein transporter to move across a concentration gradient, but its still random movement.

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14
Q

a transporter channel?

A

An opening in which molecules can freely pass.

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15
Q

Carrier transporter?

A

It binds to and then transports the specific molecule.

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16
Q

Aquaporins?

A

Transporters for water molecules.

17
Q

Osmosis?

A

The net movement of a solvent inversely proportional to a solute across a semipermeable membrane.

18
Q

Osmotic pressure?

A

The pressure needed to halt osmosis.

19
Q

Active transport? (2•)

A

•The movement of molecules via ATP, molecules can go with or against a concentration gradient. The ATP “facilitated protein channel” called a pump.
•cells pump small ions to one side of the membrane resulting in a concentration gradient of charge.

20
Q

Electrical gradient?

A

A gradient with a change of energy across the membrane.

21
Q

Electrochemical gradient?

A

A gradient with a change of energy and concentration across a membrane.

22
Q

Secondary active transport?

A

Movement facilitated by protons, not ATP.

23
Q

Hypertonic solution?

A

A higher solute concentration outside than inside the cell; the cell shrinks.

24
Q

Hypotonic solution?

A

A lower solute concentration outside than inside the cell; the cell bursts.

25
Q

Isotonic?

A

The same solute and solvent concentrations.

26
Q

Turgor pressure?

A

Force exerted by water pressing against an object like the cell wall. It results by osmosis.

27
Q

What is the benefit of turgor pressure?

A

It can stop osmosis during a hypotonic solution as the cell wall increases that block the holes that facilitate permeability.

28
Q

In osmosis, water moves from a?

A

From a low solute concentration to a high solute concentration and from a high water concentration to a low water concentration.

29
Q

What would happen to the polar solvent if you add non-polar solute?

A

The non-polar solute would restrict rotation of the polar solvent because the non-polar solute would restrict PD bonds from occurring between polar solvent molecules.

30
Q

The hydrophobic effect?

A

Water molecules will loose entropy and will loose stability if hydrophobic molecules are more spread because the rotation of the water molecules will be more fixed.

31
Q

Why does water favour unsaturated lipids?

A

Because they are packed together less tightly making the membrane more fluid.

32
Q

What happens to free energy and entropy when the cell membrane begins forming?

A

Entropy of water increases while free energy decreases (is lost).

33
Q

What is the reason why ions have a hard time getting past the lipid bilayer?

A

Hydration shells: ions carry a huge quantity of water molecules that make them look so much bigger.