Lecture 3.1 P2 Flashcards
Assistive reproducitve technology
Infertility drugs
Intrauterine insemination
IVF - in vitro fertilization
Fertility drugs are the primary treatment for
Ovulation failure
What does clomid do
Stimulates the pituitary gland to secrete FSH
Can be followed by hCG at the time of ovulation to help maintain the pregnancy
Pergonal is what
Natural horomone derived from the urine of postmenopausal women
Comprimised of FSH and LH
Used if clomid doesnt work
Complications of fertility drus
Ovarian hyperstimulation syndrome
Can lead to multiple huge cysts
Monitoring of follicular growth with
Serial US
Recrutiment: at the beginning of the menstural cycle ___-____ follicles start to grow
3-11
At 5-7 days one of the follciles will begin to show
Dominance and the rest will become acretic (regress)
The dominant follicle will reach __ -___mm just before ovulation
17-27mm
The antral (resting follicles) are _____ -_____ mm
5-10 mm
Intrauterine insemination
If the cause of infertility is unexplained
In vitro fertilization
Physical obstruction
The ovum doesnt successfully transfer to the site of fertilization
Zygote cant successfully travel to endomettial cavity
4 steps to IVF
Step 1: controlled ovarian hyperstimulation
Step 2: Follicular aspiration
Step 3 : IVF
Step 4: Embryo transfer
Step. 1: hyperstimulation of ovary by
Clomiphene citrate
Step 2: follicular aspiration occurs by
US guided needle inserted into follicle + suction to remove follicular fluid
Several ovum removed
STEP 3 IVF processes
Sperm injected into cell
Grown for 3-5 days
Step 4 embryo transfer
Using a catheter, embryo is transferred directly to uterine lining
Can involve more than one embryo
Embrro transfer is the most common
IVF procedure
Other methods other than embryo transfer
Gamete intrafallopian transfer GIFT
Zygote intra fallopian transfer ZIFT
What happens in ZIFT
The fertilized eggs are placed in the fallopian tubes within 24 hours of fertilization
What happens with GIFT
The sperm and eggs are mixed together before inserted and with luck it becomes fertilized in the tubes (in vivo)
Why are GIFT and ZIFT used
Closer to natural conception
Multifetal reduction
For couples with 3 or more fetuses, involve saline injection into the gestational sac
