Lecture 3

Question 1

What are the principles of sampling? (8)

Answer 1

1. Obtain sample from site of infection & min contamination
2. Collect sample at the correct time
3. Collect sufficient quantity of sample (but not too much)
4. Use an appropriate collection device
5. Obtain cultures before administration of a/bs
6. Make smears in addition to cultures
7. Label
8. Don’t put others in danger

Question 2

What is the goal of a diagnostic micro lab?

Answer 2

To provide therapeutic guidance

Question 3

Susceptible

Answer 3

When a patient has an infection with a susceptible organism, there is a high likelihood of clinical success when treated with a drug according to the drug label indication

Question 4

Resistant

Answer 4

When a patient has an infection with a resistant organism, clinical failure is predicted when treated with a drug according to the label indication

Question 5

Min inhibitory [ ] (MIC)

Answer 5

lowest [ ] of an a/b which inhibits bacterial growth

Question 6

Intrinsic resistance

Answer 6

Constitutive for an organism

Question 7

Acquired resistance

Answer 7

Organisms don’t have something hereditary, they acquired something that makes them “super”

Question 8

What are the susceptibility test models? (2)

Answer 8

Categorial methods

Quantitative methods

Question 9

Categorial susceptibility test methods

Answer 9

Indicates if organism is susceptible or resistant

Question 10

Quantitative susceptibility test methods

Answer 10

Indicates how susceptible or resistant an isolate is

Achieved by acquiring an MIC