Lecture 20 Flashcards
Echinacea MOA
immunostimulant, increases macrophage proliferation and phagocytosis and increases T lymphocytes
antiviral activity
anti inflammatory
anti bacterial
ADR Echinacea
avoid with ragweed allergy, and pts with auto-immune disorders
Drug interactions echinacea
inhibits CYP 3A4, immunosupressants
Elderberry MOA
anti-oxidant, antiviral, anti-inflammatory
Zinc MOA
zinc blocks cold virus from binding to receptor, inhibiting viral replication and modulating immune function
ADR zinc
metallic taste, dry mouth
drug interactions zinc
complexes with tetracyclines, quinolones, etc.
take 2 hrs before, or 4-6 bhours after zinc
citric acid does what with zinc
decreases ionization
Vitamin C
antioxidant, immunstimulant
oregano oil?
not effective
manuka honey MOA
anti bacterial MGO
GINSENG MOA
immune modulating effects, increases response to vaccination
Cold FX
ineffective of treatment
barely any decrease in prevention
ADR ginseng (cold fx)
insomnia
drug interactions ginseng
warfarin, decreases clearance of warfarin
does echinacea help with treatment/prevention
treatment no, prevention yes - reduction
andrographics treatment/prevention
best evidence for treatment when combined with eleuthero
prevention: works against influenza
which zinc lozenges have best evidence
gluconate or acetate
does zinc help with treatment/prevention
yes, decreasing duration and severity for treatment, no use for prevention
elderberry effective at prevention/treatment?
yes for treatment, no for prevention
