CV 3 Flashcards

1
Q

What is blood pressure

A

Cardiac output x total peripheral resistance

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2
Q

what is cardiac output

A

heart rate x stroke volume

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3
Q

what is total peripheral resistance

A

resistance in blood flo win the arterioles

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4
Q

the ability of pacemaker cells to spontaneously depolarize is determined by what

A

Pacemaker current (Ir) carried by slow Na influx through the HCN channel. It is an inward current, responsible for starting the depolarization phase.

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5
Q

How does HCN work

A

cAMP binds to HCN channel, allowing Na+ influx

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6
Q

Which hormones increase cAMP

A

NE - increase heart rate

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7
Q

which hormones decrease cAMP

A

Acetylcholine - decrease heart rate

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8
Q

what is stroke volume

A

end diastolic volume - end systolic volume

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9
Q

what is preload

A

the degree to which ventricles are stretched. Represends ventricular end diastolic volume

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10
Q

the more stretch of muscle fibers, the..

A

greater force in contraction

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11
Q

contractility

A

the intrinsic ability of the heart to contract dependent on the amount of Ca and the binding between actin and myosin

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12
Q
A
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