Lecture 17 Flashcards
how is RSV transmitted
inhalation or contact with infected ppls respiratory secretions
what is the reproductive number of RSV
3
RSV seasonality
starts late oct, peaks jan, lingers till may
when do you get the most RSV infection
19 months - 5 year old. Dont have innate immunity yet
greater than 70 years of age due to declining immunity
what increases risk for severe infection, hospitalization, and mortality from RSV complications
advanced age
frailty
chronic medical conditions
are reinfections possible with RSV
yes!
how long are adults infectious for
3-8 days
common symptoms
sore throat, voluminous rhinorrhea, cough, nasal congestion, headache, cough
what does progression of RSV typically cause
acute bronchitis or pneumonia
what can severe RSV cause
CHF and asthma/COPD exacerbations
what are CV complications of RSV
MI, CHF, exacerbations of heart failure arrhythmia MI
among healthy adults aged 65 plus, and adults with chronic lung or heart disease RSV accounted for
11.4 % of hospitalizations for COPD and 7.2% of hospitalizations for asthma
Gold standard for RSV diagnostic testing
molecular PCR testing
what is the clinical way of testing
rapid antigen testing
RSVPreF vaccine type and age group
GSK product (has adjuvant in it), pfizer
subunit RSV in 60+
