lecture 19 Flashcards

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1
Q

Viruses

A
  • Acellular
  • most are composed only of nucleic acids and some proteins
  • consist of a central core of DNA and RNA surrounded by a capsid of proteins
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2
Q

Why can’t viruses do?

A
  • Regulate transport of materials into and out of themselves
  • perform any metabolic functions
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3
Q

Virus: obligate intracellular parasites

A
  • They use the host cell’s DNA replication and protein synthesis machinery to reproduce themselves
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4
Q

Phage (bacteriophage)

A
  • Reproduces immediately and kills the host cell
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5
Q

lytic cycle

A

cell bursts and releases progeny viruses

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6
Q

Lysogenic cycle

A

Postpones reproduction by integrating its nuclei acids into the host cell’s genome

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7
Q

Retrovirus (HIV)

A
  • Reverse transcriptase
  • facilitates RNA
  • directed DNA synthesis
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8
Q

DNA provirus

A
  • produced
  • integrated permanently into the host’s genome
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9
Q

What happens when proviral DNA is activated?

A

New virions are produced

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10
Q

Reserve transcriptase

A

RNA into DNA

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11
Q

Lyric viruses

A

Polio, rabies, measles, colds

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12
Q

What phase do viruses have?

A
  • Lyric phases
  • some have Lysogenic phase
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13
Q

EBV

A
  • Lystic leads to mono
    -Lysogenic leads to lymphoma
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14
Q

HPV

A
  • Lytic lead to genital warts
  • Lysogenic can lead to cervical cancer
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15
Q

Herpes

A

Lytic and latent Lysogenic properties

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16
Q

HPV

A
  • Virus known to cause cancer
  • HPV vaccine prevents infection by the virus and therefore cancer
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17
Q

Oncolytic viruses

A

Viruses engineered to express cancer suppressing genes in human tissues

18
Q

Where do prokaryotes live?

A
  • Every known niche in the world
  • land, sea, air
  • hot and freezing
19
Q

Ecological niche

A
  • Not a place
  • refers to resources available in a territory
20
Q

Prokaryotes, archea and bacteria: shared characteristics

A
  • most are small and unicellular
  • no nucleus
  • one circular chromosome
  • most have cell wall
  • ribosomes structure is different than eukaryotes’
    Reproduce asexually (no meiosis)
21
Q

Prokaryotes, archea and bacteria: shared characteristics

A
  • most are small and unicellular
  • no nucleus
  • one circular chromosome
  • most have cell wall
  • ribosomes structure is different than eukaryotes’
    Reproduce asexually (no meiosis)
22
Q

Two types of prokaryotes

A
  • Bacteria
  • archaea
23
Q

Variety of shapes of archaea

A

Rods, cocci’s spirilla, filaments

24
Q

Extremophiles (archaea)

A

Typically found in extreme environments

25
Q

Methanogens (archaea)

A
  • Found in anaerobic environments
  • release methane as a waste product of cellular metabolism
26
Q

Where do methagens (archaea) live?

A
  • in mud at the bottom of swamps because lack of oxygen
  • in the intestinal tracts of animals (cows)
27
Q

Anaerobic

A

No oxygen

28
Q

Extreme halophiles (archaea)

A
  • Like salt
  • found in the Dead Sea and other extremely saline lakes
29
Q

Extreme theronophiles ( archaea)

A
  • Grow in hot environments
  • found in deep sea vent areas and in hot-springs
30
Q

Shape of prokaryotes

A
  • Spheres (cocci)
  • rods (bacilli)
  • spirals
31
Q

Cocci (arrangement)

A
  • Coccus (ball)
  • single=coccus
  • 2 together =diplococci
  • chains = streptococci
  • clusters = straphlococci
32
Q

Bacillus (rod - shaped)

A
  • Single rod (bacillus)
  • chains = streptobacilli
  • plural =bacilli
33
Q

Spirochetes

A
  • Gram-negative
    -Motile
  • chemoheterotrophic
  • have unique axial filaments (modified flagella) that rotate
34
Q

Types of spirochetes

A
  • Many human parasites
  • Some pathogens (syphilis,Lyme disease)
  • others free living
35
Q

Important feature in all prokaryotic alls

A

Cell wall

36
Q

What do cell walls do in prokaryotic alls?

A
  • Maintains cell shape
  • provides physical protection
  • prevents the cell from bursting in a hypotonic environment
37
Q

What are entraryote cell walls made of?

A

Cellulose or chitin

38
Q

What do bacterial cell walls contain

A

Peptidoglycan (network of sugar polymers cross-linked by polypeptides)

39
Q

What is contained in archaea?

A
  • polysaccharides and proteins
    -Lack peptidoglycan
40
Q

Use of gram stain

A

Scientists classify many bacterial speeds into gram-positive and gram-negative groups based on cell wall composition

41
Q

Gram-negative bacteria

A
  • Less peptidoglycan (thin wall)
  • outer membrane can be toxic
    Thick outer layer of lipids and carbohydrates
  • are more likely to be antibiotic resistant
  • do not retain purple stain (remain red in colours