Lecture 18: IBD Flashcards
True or False: Both Crohn’s Disease and Ulcerative Colitis are characterized by abnormal or heightened immune response
TRue
True or False: Both Crohn’s Disease and Ulcerative Colitis are characterized by abnormal or heightened immune response
True
Which three genes are implicated in Crohn’s Disease and Ulcerative Colitis?
NOD2
ATG16L1
IRGM
The fact that IBD is greater in monozygotic twins (as opposed to dizygotic twins) suggests….
IBD is more genetically determined
What are four plausible mechanisms for IBD?
- Host response to luminal antigens
- Epithelial cell dysfunction
- Th1/Th17 activation
- Changes in microbiota
True or False: UC can occur in small and large intestines
False - Chron’s can!
Skip lesions, transmural inflammation, deep ulcers, fistulas, and granulomas are features of…
A. Chron’s Disease
B. UC
A. Chron’s Disease
Crohn’s Disease (CD)
ok
True or False: UC is localized to colon and is associated with bloody stool, weight loss, loose stool, flares/remission
True
What is shown here?
UC
These features describe which condition?
UC
Functions of intestinal bacteria?
- Makes B complex and K vitamins
- Immune regulation
- Health and disease
- Stimulates cell growth
True or False: Compared to the stomach, there is more bacteria in the colon and it is more diverse
True
True or False: Depending on the organ/location, there is different bacterial content present
True
