L24: STD - shortened Flashcards
Lymphogranuloma Venereum (LGV), Genital Herpes, Syphilis, and Chancroids are:
A. Genital Ulcer Disease
B. Warts, Papillomas
C. Cervicitis, Urethritis, and PID
A. Genital Ulcer Disease
True or False: N. gonorrhea and Chlyamydia belong to Cervicitis, Urethritis, and PID
True
Which gram-negative spirochete—which is ONLY visible by dark field microscopy—pathogen is responsible for causing syphilis?
Treponema pallidum
Primary syphilis is the initial latent period while tertiary syphilis is associated with which three symptoms?
- Gumma
- Cardiovascular Syphilis
- Neurosyphilis
Painless induration is associated with which stage of syphilis?
A. Primary stage
B. Secondary stage
C. Tertiary stage
A. Primary stage
True or False: Hard chancre/genital ulcer develops at point of entry in primary stage of syphilis
True
Which stage of syphilis resolves with or without treatment and highly infectious lesions?
Secondary Stage
Which stage is patient still infectious with syphilis? when are they no longer infectious?
Early Latent = still infectious
Late Latent = not infectious
When do most secondary syphilis relapses occur?
A. Early Latent
B. Late Latent
A. Early Latent
Which stage of syphilis is associated with slow, progressive inflammatory disease affecting any organ system + is REFRACTORY to abx therapy ?
Tertiary (Late) Stage
Which form of syphilis can be transmitted in utero, via placenta, at any stage of pregnancy
Syphilis Congenital Form (CS)
True or False: A patient is 2 years of age with congenital form of syphilis. They have the perinatal form
True
Hard chancre and genital ulcer suggests….
Syphilis
Which drug can treat all three stages of syphilis?
A. Methotrexate
B. Penicillin
B. Penicillin
How does one prevent congenital syphilis?
Benzathine penicillin >1 month prior to birth
____: A reaction that occurs s/p initial syphilis treatment, associated with flu-like symptoms
Jarisch-Herxheimer Reaction
True or False: Jarisch-Herxheimer Reaction usually occurs s/p initial syphilis treatment and is an endotoxic shock like response
True
- Rarely fatal
- Related to release of components by dead or dying trponemes
Which pathogen causes soft, but painful, chancre?
H. ducreyi
Chancroid increases the risk of developing __
HIV
A patient has a painful, soft ulcer and local lymphoadenitis. Upon gram staining, you see a “school of fish arrangement,” which suggests…
Chancroid
Which pathogen causes Lymphogranuloma Venereum?
A. Treponema pallidum
B. Chlamydia trachomatis
B. Chlamydia trachomatis
Three stages of LGV?
Primary Lesion
Inguinal (secondary) syndrome
Tertiary Stage
Which pathogen causes herpes? Can it be latent?
HSV
- Yes!
Syncytia formation suggests which condition? Treatment (but not cure)?
Genital Herpes
- Acyclovir
__ is the most prevalent STD
HPV
True or False: In HPV, cervical papillomas and condyloma acuminatum can result in benign mucosa dysplasias
True
Cervical papillomas
- mucosal HPV
Condyloma Acuminatum
- cutaneous HPV
Koilocytosis is a feature of __
A. Genital Herpes
B. HPV
C. Gonorrhea
D. Chlamydia
B. HPV
Treatment for HPV?
Cidofovir cream
True or False: There is a vaccine to prevent HPV
True
True or False: Patients are often co-infected with N. gonorrhoeae and Chlamydia trachomatis
True
True or False: N. gonorrhoeae is gram (-) diplococci while C. trachomatis is obligate intracellular bacterium
True
True or False: Cervicitis can result from chlamydia
True
PID is a complication of infection with ___ and ___
Gonorrhea and Chlamydia
What complications can arise if a newborn develops Gonorrhea-Chlamydia?
Acute conjunctivitis – could lead to eventual blindness
How to tx Gonorrhea? Chlamydia?
Gonorrhea: Ceftriaxone
Chlamydia: Tetracycline
How is Trichomoniasis treated? How is it acquired?
Metronidazole
- Douching
If you have a (+) Whiff/Sniff Test and (+) Clue cells, this suggests which condition?
Bacterial Vaginosis (BV)
True or False: There is an absence of inflammatory signs and signals in BV
True
___: A condition that arises due to NF in vagina, leading H2O2 producing Lactobacilli replaced by other. There is no inflammation associated with this condition.
BV
