L24: STD - shortened

Question 1

Lymphogranuloma Venereum (LGV), Genital Herpes, Syphilis, and Chancroids are:
A. Genital Ulcer Disease
B. Warts, Papillomas
C. Cervicitis, Urethritis, and PID

Answer 1

A. Genital Ulcer Disease

Question 2

True or False: N. gonorrhea and Chlyamydia belong to Cervicitis, Urethritis, and PID

Answer 2

True

Question 3

Which gram-negative spirochete—which is ONLY visible by dark field microscopy—pathogen is responsible for causing syphilis?

Answer 3

Treponema pallidum

Question 4

Primary syphilis is the initial latent period while tertiary syphilis is associated with which three symptoms?

Answer 4

1. Gumma
2. Cardiovascular Syphilis
3. Neurosyphilis

Question 5

Painless induration is associated with which stage of syphilis?
A. Primary stage
B. Secondary stage
C. Tertiary stage

Answer 5

A. Primary stage

Question 6

True or False: Hard chancre/genital ulcer develops at point of entry in primary stage of syphilis

Answer 6

True

Question 7

Which stage of syphilis resolves with or without treatment and highly infectious lesions?

Answer 7

Secondary Stage

Question 8

Which stage is patient still infectious with syphilis? when are they no longer infectious?

Answer 8

Early Latent = still infectious
Late Latent = not infectious

Question 9

When do most secondary syphilis relapses occur?
A. Early Latent
B. Late Latent

Answer 9

A. Early Latent

Question 10

Which stage of syphilis is associated with slow, progressive inflammatory disease affecting any organ system + is REFRACTORY to abx therapy ?

Answer 10

Tertiary (Late) Stage

Question 11

Which form of syphilis can be transmitted in utero, via placenta, at any stage of pregnancy

Answer 11

Syphilis Congenital Form (CS)

Question 12

True or False: A patient is 2 years of age with congenital form of syphilis. They have the perinatal form

Answer 12

True

Question 13

Hard chancre and genital ulcer suggests….

Answer 13

Syphilis

Question 14

Which drug can treat all three stages of syphilis?
A. Methotrexate
B. Penicillin

Answer 14

B. Penicillin

Question 15

How does one prevent congenital syphilis?

Answer 15

Benzathine penicillin >1 month prior to birth

Question 16

____: A reaction that occurs s/p initial syphilis treatment, associated with flu-like symptoms

Answer 16

Jarisch-Herxheimer Reaction

Question 17

True or False: Jarisch-Herxheimer Reaction usually occurs s/p initial syphilis treatment and is an endotoxic shock like response

Answer 17

True
- Rarely fatal
- Related to release of components by dead or dying trponemes

Question 18

Which pathogen causes soft, but painful, chancre?

Answer 18

H. ducreyi

Question 19

Chancroid increases the risk of developing __

Answer 19

HIV

Question 20

A patient has a painful, soft ulcer and local lymphoadenitis. Upon gram staining, you see a “school of fish arrangement,” which suggests…

Answer 20

Chancroid

Question 21

Which pathogen causes Lymphogranuloma Venereum?
A. Treponema pallidum
B. Chlamydia trachomatis

Answer 21

B. Chlamydia trachomatis

Question 22

Three stages of LGV?

Answer 22

Primary Lesion
Inguinal (secondary) syndrome
Tertiary Stage

Question 23

Which pathogen causes herpes? Can it be latent?

Answer 23

HSV
- Yes!

Question 24

Syncytia formation suggests which condition? Treatment (but not cure)?

Answer 24

Genital Herpes
- Acyclovir

Question 25

__ is the most prevalent STD

Answer 25

HPV

Question 26

True or False: In HPV, cervical papillomas and condyloma acuminatum can result in benign mucosa dysplasias

Answer 26

True

Cervical papillomas
- mucosal HPV

Condyloma Acuminatum
- cutaneous HPV

Question 27

Koilocytosis is a feature of __
A. Genital Herpes
B. HPV
C. Gonorrhea
D. Chlamydia

Answer 27

B. HPV

Question 28

Treatment for HPV?

Answer 28

Cidofovir cream

Question 29

True or False: There is a vaccine to prevent HPV

Answer 29

True

Question 30

True or False: Patients are often co-infected with N. gonorrhoeae and Chlamydia trachomatis

Answer 30

True

Question 31

True or False: N. gonorrhoeae is gram (-) diplococci while C. trachomatis is obligate intracellular bacterium

Answer 31

True

Question 32

True or False: Cervicitis can result from chlamydia

Answer 32

True

Question 33

PID is a complication of infection with ___ and ___

Answer 33

Gonorrhea and Chlamydia

Question 34

What complications can arise if a newborn develops Gonorrhea-Chlamydia?

Answer 34

Acute conjunctivitis – could lead to eventual blindness

Question 35

How to tx Gonorrhea? Chlamydia?

Answer 35

Gonorrhea: Ceftriaxone
Chlamydia: Tetracycline

Question 36

How is Trichomoniasis treated? How is it acquired?

Answer 36

Metronidazole
- Douching

Question 37

If you have a (+) Whiff/Sniff Test and (+) Clue cells, this suggests which condition?

Answer 37

Bacterial Vaginosis (BV)

Question 38

True or False: There is an absence of inflammatory signs and signals in BV

Answer 38

True

Question 39

___: A condition that arises due to NF in vagina, leading H2O2 producing Lactobacilli replaced by other. There is no inflammation associated with this condition.

Answer 39

BV