lecture 12: cardiac output Flashcards
normal heart rate
60-100bpm
normal stroke volume
50-100mls
cardiac output equatio
CO = HR X SV
stroke volume equation
SV = End Diastolic Volume (EDV) - End Systolic Volume (ESV)
preload
force that stretches the cardiac muscle prior to contraction. before contraction, more blood returns to heart, which increase pressure causing ventricles to stretch to accomodate. increase in preload increases stroke volume
frank starling law
“the energy of contraction of the ventricle is a function of the
initial length of the muscle fibres comprising its walls.”
*meaning, increasing the stretch of the ventricles will increase the force of contraction”
factors affecting preload
∆ Venous return
∆ Blood volume
∆ Filing time
∆ Respiratory pump
∆ Compliance eg MI damage
contractility
the force of contraction of the heart. its peroformans at a given preload and afterload. more contractility means more calcium for contraction means increase in stoke volume. norepinephrine through sympathetic increases stroke volume
afterload
The amount of pressure that the heart needs to exert to eject the blood during ventricular contraction. pressure in the aorta that the pressure in ventricle needs to overcome. increase in afterload increases ESV and deceases SV