Lecture 11: Hypertension Drug Treatments

Question 1

examples and side effects of ACE inhibitors

Answer 1

• ramipril
• dry cough due to bradykinin build-up
• first dose hypotension
• renal impairment
• potential hyperkalaemia

Question 2

examples and side effects of angiotensin receptor blockers

Answer 2

• losartan

- minimal side effects

Question 3

examples and uses of aldosterone antagonists

Answer 3

• spironolactone
• add on for resistant hypertension
• frontline for primary aldsteronism

Question 4

examples and side effects of calcium channel blockers

Answer 4

• amlodipine for smooth muscle channels
• verapamil for cardiac channels
• diltiazem for cardiac channels
• causes flushing and headaches
• causes peripheral oedema

Question 5

examples and side effects of thiazide and thiazide like diuretics

Answer 5

• indapamide
• hypokalaemia
• contraindicated in diabetics

Question 6

examples and side effects of beta blockers

Answer 6

• propranolol is non-selective
• bisoprolol is selective
• can cause broncho/vaso constriction
• hypoglycaemia

Question 7

types and uses of vasodilaters

Answer 7

• alpha 1 antagonists
• K+ channel openers
• treat hypertension in benign prostatic hypertrophy