Lecture 10.17.14 (Exam #3)

Question 1

Stage 1 of catabolism

Answer 1

polymers to monomers: no ATP is made

Question 2

Stage 2 of catabolism

Answer 2

monomers to intermediates (metabolites): little ATP made

Question 3

Stage 3 of catabolism

Answer 3

intermediates to rawest form (CO2): lots of ATP

Question 4

Where is glucose for glycolysis found?

Answer 4

Liver & Muscles

Question 5

Polymer of Glucose

Answer 5

Glycogen

Question 6

If glucose is needed the _____ will release it in the ____?

Answer 6

Liver;blood

Question 7

2 hormones that affect concentration of glucose in bloodstream

Answer 7

glucagon (pancreas)

adrenaline (brain)

Question 8

Glucagon

Answer 8

hormone produced by the pancreas to raise the concentration of glucose in the bloodstream

Question 9

(LIVER)G.phosphorylase converts glycogen to _______

Answer 9

Glucose 1 phosphate (G1P)

Question 10

(LIVER)Which enzyme converts glycogen to G1P?

Answer 10

G.phosphorylase

Question 11

(LIVER)Mutase converts glucose 1 phosphate to _______

Answer 11

Glucose 6 phosphate (G6P)

Question 12

(LIVER)Which enzyme converts G1P to G6P?

Answer 12

Mutase

Question 13

G6P gets split into _____ & _____

Answer 13

glucose & 5 carbon sugar

Question 14

What are transporters used for?

Answer 14

to let glucose out of liver and into the muscle

Question 15

What are transporters?

Answer 15

membrane bound proteins that allow specific molecules to pass

Question 16

GLUT

Answer 16

transporters of glucose

Question 17

Where is GLUT 1 & 3 found?

Answer 17

every cell has these receptors

Question 18

Where is GLUT 2 found?

Answer 18

liver & pancreas

Question 19

Where is GLUT 4 found?

Answer 19

muscles & fat cells (adipose tissue)

Question 20

Where is GLUT 5 found?

Answer 20

small intestine

Question 21

(MUSCLE) ______ along with ATP is used to convert glucose to G6P

Answer 21

hexokinase

Question 22

T/F G6P can pass through GLUT

Answer 22

FALSE

Question 23

Hexokinase undergoes a _____ _____ _____and ____ is coupled with ATP?

Answer 23

dramatic conformational change; Mg+2

Question 24

Why is Mg+2 attached to ATP?

Answer 24

to stabilize negative charges

Question 25

What would happen if H2O entered the active site of hexokinase?

Answer 25

glucose would not pick up phosphate, but water instead

Question 26

What is a tactic used by an enzyme that does not want water in their active site?

Answer 26

they undergo a dramatic conformational change

Question 27

What is a competitive inhibitor of hexokinase

Answer 27

G6P

Question 28

product inhibition

Answer 28

when a product of a reaction catalyzed acts as a competitive inhibitor for an enzyme
ex. hexokinase (G6P)

Question 29

hexokinase vs. glucokinase

Answer 29

glucokinase is found in the liver and has a lower affinity than hexokinase