lecture 1 exam 1 Flashcards
the cause of dz
etiology
Define dz
any deviation from the normal structure or function – May or may not have characteristic clinical signs – May affect the whole body or any of its parts – Of known or unknown cause
pathogenisis
= sequence of events from initial stimulus to ultimate expression of disease
molecular and morphological changes
biochemical and structural alterations induced in cells and organs of the body
clinical signs resulting from functional abnormalities of affected tissues
clinical manifestations
What stage of dz is this
pathogenisis
True or false this is an example of molecular change of dz?
false
morphological change
is it possible for this molecular change to result in clinical signs
yes
coughing cows from pasturella pnuemonia
5 pathological processes
Degeneration/Necrosis • Inflammation & Repair • Circulatory Disorders • Disorders of Growth • Deposits & Pigmentations
concise statement or conclusion concerning the nature, cause, or name of a disease
daignosis
defne prognosis
outcome
dz name
– aims to encapsulate the host, morphology, and cause of disease; ex: Bovine viral diarrhea
What can you use to come up with a Differential diagnoses (DDx)
Damnit-V scheme
Define lesion
any morphological change in tissues during disease – Lesions caused by disease manifest morphologically as alterations in color, shape, size, texture, etc… – Microscopic or Macroscopic
Explain the difference between Mdx and Edx
Morphologic diagnosis (MDx) – Includes pathological process, location, distribution, duration & severity •
Etiologic diagnosis (Edx) – Includes pathological process, location, and cause
lesions – characteristic of a specific disease
Pathognomonic lesions
Example of a pathognomonic lesion… Kidney from a puppy that died 2 weeks after birth: Which answer is the description of kidney?
A) Multifocal necro-hemorrhagic nephritis
B) Canine herpesvirus-1
C) Herpesviral nephritis
D) infection with canine herpesvirus-1 viral replication in endothelial cells endothelial cell injury and inflammatory response multifocal necro-hemorrhagic nephritis
E) Fading puppy syndrome (or Canine Herpes)
F) Multifocally 2-4mm descrete dark red foci throghout cortical surface
F
Example of a pathognomonic lesion… Kidney from a puppy that died 2 weeks after birth: Which answer is the pathogenisis? How do you know?
A) Multifocal necro-hemorrhagic nephritis
B) Canine herpesvirus-1
C) Herpesviral nephritis
D) infection with canine herpesvirus-1 viral replication in endothelial cells endothelial cell injury and inflammatory response multifocal necro-hemorrhagic nephritis
E) Fading puppy syndrome (or Canine Herpes)
F) Multifocally 2-4mm descrete dark red foci throghout cortical surface
D
Starts with cause and ends with lesion
Example of a pathognomonic lesion… Kidney from a puppy that died 2 weeks after birth: Which answer is the Edx?
A) Multifocal necro-hemorrhagic nephritis
B) Canine herpesvirus-1
C) Herpesviral nephritis
D) infection with canine herpesvirus-1 viral replication in endothelial cells endothelial cell injury and inflammatory response multifocal necro-hemorrhagic nephritis
E) Fading puppy syndrome (or Canine Herpes)
F) Multifocally 2-4mm descrete dark red foci throghout cortical surface
C
Example of a pathognomonic lesion… Kidney from a puppy that died 2 weeks after birth: Which answer is the Dz name?
A) Multifocal necro-hemorrhagic nephritis
B) Canine herpesvirus-1
C) Herpesviral nephritis
D) infection with canine herpesvirus-1 viral replication in endothelial cells endothelial cell injury and inflammatory response multifocal necro-hemorrhagic nephritis
E) Fading puppy syndrome (or Canine Herpes)
F) Multifocally 2-4mm descrete dark red foci throghout cortical surface
E
Example of a pathognomonic lesion… Kidney from a puppy that died 2 weeks after birth: Which answer is the Mdx?
A) Multifocal necro-hemorrhagic nephritis
B) Canine herpesvirus-1
C) Herpesviral nephritis
D) infection with canine herpesvirus-1 viral replication in endothelial cells endothelial cell injury and inflammatory response multifocal necro-hemorrhagic nephritis
E) Fading puppy syndrome (or Canine Herpes)
F) Multifocally 2-4mm descrete dark red foci throghout cortical surface
A
Example of a pathognomonic lesion… Kidney from a puppy that died 2 weeks after birth: Which answer is the cause/ Etiology?
A) Multifocal necro-hemorrhagic nephritis
B) Canine herpesvirus-1
C) Herpesviral nephritis
D) infection with canine herpesvirus-1 viral replication in endothelial cells endothelial cell injury and inflammatory response multifocal necro-hemorrhagic nephritis
E) Fading puppy syndrome (or Canine Herpes)
F) Multifocally 2-4mm descrete dark red foci throghout cortical surface
B
How do you tell the difference between Mdx and Edx
Edx includes the cause
