Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Path 1 > exam 3 pigments > Flashcards

exam 3 pigments Flashcards

1
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

free hemogobin from damaged RBC is picked up in circulation by

A

hapten

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What cell in the spleen/liver breaks hemoglobin into 3 parts

A

macrophage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

3 products of hemoglobin

A

iron

globin

heme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How is heme processed?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How is unconjugated bilirubin processed?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Too much bilirubin in the blood

A

hyperbilirubinemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

bilirubinemia >> 2 mg/dl you get

A

jaundice

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Yellow discoloration of tissue or fluid

A

Jaundice or Icterus = increased bilirubin in tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

True or false

use fat to assess, especially livestock, corn fed chickens, monkeys.

A

false

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How does hyperbilirubinemia (icterus) happen?

A
  1. Prehepatic hyperbilirubinemia
  2. Hepatic hyperbilirubinemia
  3. Posthepatic hyperbilirubinemia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

hemolysis is an etiology of ____ jaundice

A

pre hepatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Get this black kidney because excessive _____ filtered through the kidney is toxic to the kidney

A

hemoglobin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Red-brown coloration of kidney and urine – Pink serum

A

Hemoglobinuria due to intravascular haemolysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Red-brown coloration of kidney and urine – Pink serum

A

Hemoglobinuria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

tylenol causes jaundice in cats what are eitologis are there?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Prehepatic, Hepatic, or Posthepatic?

A

Prehepatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Prehepatic, Hepatic, or Posthepatic?

A

Prehepatic - IMHA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Prehepatic, Hepatic, or Posthepatic?

A

Hepatic – infectious canine hepatitis (adenovirus)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Prehepatic, Hepatic, or Posthepatic?

A

Posthepatic – biliary calculus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Iron stored intracellularly as ferritin (bound to apoferritin) • Gross – Must have a lot to impart gross brown color

A

hemosideran

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Stains blue-black with prussian blue / Perls

A

hemosideran

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Hemosideran accumulation can be __ or __

A
  1. Local: Chronic congestion Hemorrhage 2. Widespread: Hemolysis Inherited disorders of Fe storage
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

“Heart failure cells” – hemosiderin-laden macrophages within alveoli. Local or widespread?

A

Localized hemosiderosis due to chronic congestion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

This is ____ accumuation of hemosideran due to hemolysis

A

generalized

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Pink-red discolored bones and teeth – Fluoresces with uv light in calves, pigs, cats

A

Erythropoietic porphyria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Erythropoietic porphyria is an inherited defenciy of ____

A

uroporphyrinogen III cosynthetase  defect in heme synthesis  porphyrins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

What is this pigment

A

melanin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Disease: Flea allergy dermatitis secondaryily leads to what MDX?

A

MDx: Cutaneous hyperpigmentation (hypermelanosis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Sheep brain has developmental anomaly Mdx:

A

MDx: meningeal melanosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Sheep uterus developmental anomaly

A

MDx: endometrial melanosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Cow lungs developmental anomaly

A

MDx: pleural melanosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Pigmentation?

34
Q

Derived from the breakdown of lipids - an un-degradable remnant of breakdown of organelles • Composed of lipid complexed with protein • Commonly in found in aged cells and injured cells (“wear and tear” pigment) • Especially accumulates in postmitotic cells

A

lipofuscin

35
Q

Tissue obtains a brownish color after large amount of accumulation

A

MDx: Myocardial lipofuscinosis

36
Q

Pony lesser omentum

MDx: omental carotenoid pigmentation (EXOGENOUS PIGMENTATION)

A

Pathogenesis: vitamin A accumulates in fatty tissues and causes yellow-orange discoloration

37
Q

inhaled carbon deposits in peribronchiolar macrophage aggregates

A

MDx: pulmonary anthracosis

“Pneumoconiosis” = inhaled dust, anthracosis is a subtype of this

38
Q

African green monkey lung

A

MDx: pulmonary anthracosis Pathogenesis: inhaled carbon deposits in peribronchiolar macrophage aggregates “Pneumoconiosis” = inhaled dust, anthracosis is a subtype of this

39
Q

sheep liver

A

MDx: chronic cholangitis & biliary parasitic hematin

40
Q

Macaque lung

A

MDx: chronic bronchiolitis and parasitic hematin & lung mites

41
Q

blue indicative of

A

ingestion of certain anticoagulant rodenticides

42
Q

this happens to puppies of moms who have been given ___ during pregnancy

A

tetracycline

43
Q

this is a mineral deposit of ___

44
Q

Gritty white deposit

45
Q

Lungs – Basophilic intracellular and extracellular pleomorphic granular material

46
Q

Kidney – Basophilic granular material within glomerular and tubular basement membranes and renal tubular epithelial cells

47
Q

what stains black with vonkossa

48
Q

2 types of calcification

49
Q

Local deposition of calcium in areas of injury • Especially necrotic fat – calcium ions interact with fatty acids, producing insoluble calcium soaps (“saponification”) • Also muscle, granulomas, dead parasites

50
Q

Widespread deposition of calcium in otherwise normal tissues • Caused by hypercalcemia • Predilection sites – vascular intima/adventitia – gastric mucosa – renal tubular epithelium – pulmonary interstitium – basement membranes

A

metastatic

53
Q

cause of hypercalcemia

A

*vitamin D deficiency (normally produced in kidney) and hyperphosphatemia (will precipitate out Ca)  PTH production  hypercalcemia

54
Q

Dystrophic vs Metastatic?

A

metastatic

55
Q
A

dystrophic

56
Q
A

metastatic

57
Q

hyperadrenocorticism or long term corticosteroid treatment

A

Calcinosis cutis

58
Q

Fibrils made of stacked β -pleated sheets • Can be formed by lots of different protein monomers • Deposited and accumulates in extracellular space – COMPRESSION ATROPHY of adjacent tissues

59
Q

Enlarged, firm organs with waxy appearance – Stains blue violet when treated with iodine + sulfuric acid • Histo – Amorphous homogenous eosinophilic extracellular material (“hyaline”)

60
Q

Amorphous homogenous eosinophilic extracellular material (“hyaline”) – Stains pink and has green birefringence with polarized light when stained with Congo Red

61
Q

Which 2 most important

62
Q

A dog that you treated for protein losing nephropathy…..

63
Q
A

Glomerular amyloidosis

64
Q

Pathogenesis of ‘reactive systemic amyloidosis’: Chronic inflammation  liver produces SAA in response to IL-4 & IL-6  spontaneous conversion of SAA to AA  formation of amyloid fibrils

A

Most common form in animals Hereditary in sharpeis and abyssinians Kidney, liver, spleen, lymph nodes

65
Q

accumulation of uric acid in tissues

66
Q

what species No uricase; uric acid is the end product – Get gout from decreased renal function, dehydration

A

birds reptiles

67
Q

Get gout from diet, genetic disorders, chemotherapy in what species

69
Q

Chalky white foci on surface of visceral organs and serous membranes (liver, myocardium, spleen, pleura, air sacs, etc…) – May involve soft tissues around joints • Histo – Needle-like clear spaces (crystals dissolve out in processing) – “Tophi” - granulomatous inflammation surrounding deposit

70
Q

?

A

visceral gout

71
Q
A

visceral gout

74
Q
A
  1. blood sample CBC/chem
  2. urine
  3. serum color
  4. mares botle feed
75
Q
A

renal lesions

76
Q

dystrophic or metatsatic?

A

d left m right

77
Q

White cats are predisposed to damage from ___

A

UV radiation

78
Q

Herefords are predisposed to what neoplasms?

A

squamous cell carcinoma eyelids

79
Q

gray horses are predisposed to ???

A

excessive perianal melonomas usually benign

Path 1 (19 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions