exam 3 neoplasm 4 cases

Question 1

How would you describe this lesion in this 4 yr old dog with regurgitation, intermittent fever, and lameness.

Answer 1

Protruding mucosal surface esophageal wall shaggy rough surface. Poss to peel away. Extends deep onto wall.

Question 2

Where would you want to take a biopsy from this lesion in order to create that histo slide?

Answer 2

From the firm areas near teh margins

(not the soft/necrotic areas or the hemorrhagic areas)

Question 3

Describe the cells seen, MDx, cause?

Answer 3

round/spindle mesenchymal cells suspended in eosinophillic matrix consistent with osteoid.

Mdx: esophageal osteosarcoma

Cause: Parasite spirocircolupi

Question 4

These are samples from the dog with the esophageal mass, could these symptoms be realated?

Answer 4

Yes this is osteopathy from the space occupying mass in the thoracic cavity. Pathogenisis unkknown

Question 5

Answer 5

inflam/repair

disorder of growth

NAG

Question 6

Histology from the cat fish described as exfolitic masses protruding outwards bluntly papillary cuboidal cells with distinct boarders invaded into the muscle cells, hyperchromatic nuclei histokeriosis and keratinized cytoplasm. Mdx? Etiologies?

Answer 6

MDx: squamous cell carcinoma

Etiologies: exposure carcinogens, genetics, oncogenic virus

Question 7

Answer 7

Question 8

Answer 8

Question 9

MDx?

Answer 9

carcinoma

Question 10

Answer 10

round cell tumor

tvt

Question 11

What is on your differentietials that causes hypercalcemia?

(HARD IONS)

Answer 11

Question 12

This dog Mdx: agasaca what is the most likely route of metastisis if there is a spot found on the radiograph in the upper portion of caudal abdomen?

Answer 12

lymphatic spread

Question 13

A meatloaf older cat comes in with chronic diarrhea and weight loss. You suspect lymphoma because on sx exam the intestines are thickened. How could you confirm?

Answer 13

immunohistochemistry and PARR to see if the cells accumulating are clonal