exam 3 integument part 2

Question 1

true or false

Edema – Erythema – +/- pustules, crust, vesicles are all forms of late dermatitis

Answer 1

false

early

Question 2

true or false

Scaling – Change in oiliness – Ulceration – Alopecia – Lichenification – Pigmentary change – Fibrosis/scarring are features of late dermatitis

Answer 2

true

Question 3

“pus in the skin” – usually bacterial infection involved • Superficial – epidermis and hair follicles – Disease examples • Canine superficial spreading pyoderma / Bacterial folliculitis • Impetigo (superficial pustular dermatitis) • Greasy pig disease • Dermatophilosis • Deep – deep dermis – Disease examples • Bacterial furunculosis • Abscesses

Answer 3

pyoderma

Question 4

Answer 4

a superficial pyoderma with bacterial folliculitis

Question 5

Answer 5

Dog with chin acne, a deep pyoderma with bacterial furunculosis

Question 6

Pores (follicular openings) • Hematogenous spread • Direct entry through damaged skin

Answer 6

how bacteria gets in

Question 7

predisposing factors of supporative dermitits

Answer 7

Disorders of keratinization (seborrhea) – Endocrine disease – Chronic dermatitis – allergy, parasites, etc… • Immunodeficiency • Anatomic predisposition

Question 8

why is supporative dermitits more common in dogs

Answer 8

Thin stratum corneum, lack of lipid seal of hair follicles, high skin pH

Question 9

(Superficial pustular dermatitis) • Nonfollicular pustules which develop into crusts • Prepubescent puppies – healthy otherwise • Adults – look for underlying disease

Answer 9

Impetigo

Question 10

puppy bellies can get ____

Answer 10

Impetigo

Question 11

Skin fold pyoderma • Pathogenesis: closely apposed skin surfaces → frictional trauma → moisture → opportunistic bacterial infections

Answer 11

Intertrigo

Question 12

Pathogenesis: – Self trauma  bacterial infection – Underlying pruritis – especially flea allergy dermatitis! • Gross: Moist, alopecic, slightly raised, red well-circumscribed lesions  ulceration/crusting

Answer 12

Pyotraumatic Dermatitis (“Hot Spots”) • Very common in dogs

Question 13

Fatal in neonatal pigs • Caused by Staphylococcus hyicus • Gross: erythema  pustules  crusts • Predisposing factors – other skin lesions, poor nutrition/husbandry, lacerations

Answer 13

Greasy Pig Disease (Exudative Epidermitis)

Question 14

train tracks gram positive filamentous bacteria which subdivide longitudinally and transversely • Lesions on back or distal extremities • Stimulate neutrophilic exocytosis: pustules  exudate  matting of hair/wool  alopecia • Predisposing factors – Wet weather in humid climates (“rain rot”) – prolonged wetting of skin/hair/wool allows penetration of epidermis by “zoospores

Answer 14

Dermatophilosis • Caused by Dermatophilus congolensis

Question 15

‘lumpy wool’ in sheep

Answer 15

Dermatophilosis

Question 16

Usually secondary condition • Bacterial infection of superficial follicles and adjacent skin • Gross: scaling, erythematous macules (often circular  ring shaped), papules, pustules, crusts, epidermal collarettes, alopecia

Answer 16

Canine superficial spreading pyoderma

Question 17

Answer 17

Folliculitis and furunculosis,

Question 18

Answer 18

Demodicosis • Cause: Demodex spp. mite

Question 19

Answer 19

MDx: multifocal exudative dermatitis. Generalized demodicosis with pyoderma in an adult dog

Question 20

Answer 20

MDx: neutrophilic dermatitis/folliculitis with intrafollicular mites and bacteria.

Question 21

Answer 21

Dermatophytosis • Cause: Epidermophyton, Microsporum, and Trichophyton spp. (keratinophilic fungi) • Contagious – acquired by contact with scales shed from infected animals • Colonize keratin, do not need to invade tissue to cause disease • Self-limiting in healthy animals, can become chronic/generalized in immunocompromised animals • Predisposing factors – Young or immunosuppressed – Hot/humid environments

Question 22

Answer 22

Dermatophytosis

Question 23

Answer 23

Pemphigus foliaceous

Question 24

Answer 24

Pemphigus foliaceous

Question 25

Answer 25

Proliferative dermatitis with “ballooning degeneration” & intracytoplasmic inclusion bodies Comment: Consistent with swine-pox infection

Question 26

Answer 26

swine-pox

Question 27

Sequence of lesions: macule → papule → vesicle → umbilicated pustule → crust → scar • Poxviruses have a gene whose product is similar to epidermal growth factor → epidermal hyperplasia • Many cutaneous lesions only, some systemic and fatal • Some are foreign animal diseases

Answer 27

pox virus

Question 28

Answer 28

Lamb with contagious ecthyma, early papular to vesicular phase

Question 29

Answer 29

orf

Question 30

think???????

Answer 30

Viruses!! • Early herpesvirus • Early poxvirus • Vesicular diseases – FMD, VSV, SVD, VES

Question 31

Question 32

Answer 32

VSV

Question 33

Answer 33

herpesvirus

Question 34

what virus

Answer 34

FHV1

Question 35

virus?

Answer 35

BHV2

Question 36

Answer 36

vesiculo-ulcerative mammillitis also due to a strain of BHV-2

Question 37

Answer 37

Granulomatous Dermatitis

Question 38

Answer 38

Idiopathic Sterile Granuloma and Pyogranuloma Syndrome