lect 4-skin Flashcards

1
Q

what is the largest organ of the body

A

skin

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2
Q

what are the layers of the epidermis

A

corneum, lucidum, granulosum, spinosum, basale

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3
Q

where are the stem cells located in the skin

A

stratum basale level

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4
Q

what type of cells are in the stratum basale

A

small cuboidal/low columnar

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5
Q

what layer of the skin are langerhans cells found

A

stratum basale

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6
Q

how are cells attached to neighbors in these stratum spinosum

A

via desmosomes

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7
Q

what is the most superficial nonkeratinized layer

A

stratum granulosum

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8
Q

what level of cells display apoptosis

A

stratum granulosum

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9
Q

what layer is only found in thick skin

A

stratum lucidum

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10
Q

what layer of skin has no cellular organelles

A

stratum corneum

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11
Q

what cell participates in the formation of the epidermal water barrier

A

keratinocytes

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12
Q

what are melanocytes derived from

A

neural crest

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13
Q

where are melanocytes found

A

stratum basale

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14
Q

what layer are merkel cells found in

A

stratum basale

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15
Q

where do langerhans cells originate

A

bone marrow

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16
Q

where are langerhan;s cells found

A

stratum spinosum

17
Q

what are free nerve endings sensitive to

A

pain, temperature, crude touch

18
Q

what are meissner’s corpuscles sensitive to

A

touch, pressure

19
Q

wat are merkel’s discs sensitive to

A

touch, pressure

20
Q

what are ruffini’s corpuscles sensitive to

A

stretching of skin

21
Q

what are pacinian corpuscles sensitive to

A

deep pressure, vibration

22
Q

what do first degree burns include

A

only the outer layer of skin (epidermis)

23
Q

what do second degree burns include

A

involve entire epidermis and upper layers of dermis

24
Q

what do third degree burns involve

A

destruction of entire epidermis and most of dermis (sensation may be present or deminished)

25
Q

what level of burn is highly likely to result in scarring and skin grafting

A

3rd degree

26
Q

what type of gland is involved in the formation of acne

A

apocrine

27
Q

what type of cell rapidly proliferates in psoriasis

A

keratinocytes