lect 4-skin Flashcards
what is the largest organ of the body
skin
what are the layers of the epidermis
corneum, lucidum, granulosum, spinosum, basale
where are the stem cells located in the skin
stratum basale level
what type of cells are in the stratum basale
small cuboidal/low columnar
what layer of the skin are langerhans cells found
stratum basale
how are cells attached to neighbors in these stratum spinosum
via desmosomes
what is the most superficial nonkeratinized layer
stratum granulosum
what level of cells display apoptosis
stratum granulosum
what layer is only found in thick skin
stratum lucidum
what layer of skin has no cellular organelles
stratum corneum
what cell participates in the formation of the epidermal water barrier
keratinocytes
what are melanocytes derived from
neural crest
where are melanocytes found
stratum basale
what layer are merkel cells found in
stratum basale
where do langerhans cells originate
bone marrow
where are langerhan;s cells found
stratum spinosum
what are free nerve endings sensitive to
pain, temperature, crude touch
what are meissner’s corpuscles sensitive to
touch, pressure
wat are merkel’s discs sensitive to
touch, pressure
what are ruffini’s corpuscles sensitive to
stretching of skin
what are pacinian corpuscles sensitive to
deep pressure, vibration
what do first degree burns include
only the outer layer of skin (epidermis)
what do second degree burns include
involve entire epidermis and upper layers of dermis
what do third degree burns involve
destruction of entire epidermis and most of dermis (sensation may be present or deminished)
what level of burn is highly likely to result in scarring and skin grafting
3rd degree
what type of gland is involved in the formation of acne
apocrine
what type of cell rapidly proliferates in psoriasis
keratinocytes
