LEC: Local Anesthesia Flashcards
How to local anesthetics work/mechanism of action?
Interferes with the movement of sodium ions across neronal cell membranes
What is local anesthesia?
Odd of pain sensation and midnent in an area of the body due to blockage of nerve conduction
What are four esters?
Cocaine procain chlorprocain and propraracain
What are three amides?
Lidocaine, mepivacain, bupivacaine
What are two local anesthetics?
Esters and amides
What local anesthesia only lasts a few minutes and is topical?
Esters
What local anesthetic is used for small animals?
Amides
How can you administer amides? 3
SC
sometimes IM
rarely IV
How are amides eliminated?
Metabolized by the liver
Out of the three amides, which one is the shortest lasting?
Lidocaine
How long does lidocaine last?
1 1/2 - 2 hours
How much more potent is lidocaine compared to procain?
2x
What is the most popular amide?
Lidocaine
Why is epinephrine not added to lidocaine for dysarrythmia?
Because epinephrine will increase the heart rate
How long does mepivacain last?
1.5-3 hours