Laxatives Flashcards
osmotic laxatives MOA
increase amount of fluid in bowel –> therefore soften stool
Osmotic laxatives e.g.
lactulose / movicol
Stimulant laxatives MOA
stimulate bowel to contract –> thus expel faeces
Stimulant laxatives e.g.
senna / picosulphate
Bulk forming laxatives MOA
help stool retain water and thereby soften stool
Bulk forming e.g.
Ispaghula husk
Rectal meds e.g.
glycerin supppository (stimulant)
phosphate enema (stimulant)
Pts w chronic constipation will benefit from
stool softening laxative (movicol / lactulose) but may need glycerin suppositories initially n rectal stool
Pts w post op ileus / opiod induced constipation / soft stool will benefit from
stimulant laxatives e.g. senna or picosulphate
prophylactic laxatives should be given to
pts w opiod analgesia –> esp elderly (stimulant laxative)