cancers and the more confusing bits Flashcards
1
Q
MEN1 syndrome
A
the 3 Ps
- parathyroid ( hyper due to parathyroid hyperplasia)
- pituitary
- pancreas –> insulinoma / gastrinoma
2
Q
MEN1 genetics
A
MEN1 gene
3
Q
most common presentation of MEN1
A
hypercalcaemia
4
Q
MEN2a syndrome
A
Medullary thyroid cancer AND the 2Ps
- parathyroid
- phaechromocytoma
5
Q
Men2b syndrome
A
Medullary thyrpoid cancer and 1 P
- phaechromocytomas
(+ marfanoid body habitus and neuromas)
6
Q
MEN2a genetic component
A
RET oncogene
7
Q
MEN2b genetic component
A
RET oncogene
8
Q
genetics in Lynch syndrome
A
Mismatch repair gene defect - MHS1/2
9
Q
FAP genetics
A
APC mutation
10
Q
liver mets usually come from
A
colorectal cancer
11
Q
SCLC is a
A
central lung cancer (not in apices)
12
Q
type of lung cancer seen more often in nonsmokers
A
adenocarcinoma
13
Q
pernicious anaemia predisposes to
A
gastric cancer
