haem Flashcards by Natasha Early

Q

aplastic crisis has

A

low reticulocytes

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Q

Sequestration crisis has

A

high reticulocytes

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Q

FAB classification is for

A

AML –> shows what Fx seen on blood film

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Q

JAK2 mutation

A

polycythaemia rubra vera

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Q

Philadelphia chromosome

A

t(9:22)

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Q

ALL gentics

A

philadelphia chromosome

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Q

Auer rods suggest

A

APML

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Q

APML genetics

A

t(14:17)

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Q

Down syndrome is assoc w

A

ALL

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Q

smear / smudge cells indicative of

A

CLL

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Q

RIchters transformatio

A

CLL to a high grade lymphoma

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Q

ALL blood film shows

A

blast cells

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Q

CML genetics

A

philadelphia chromosome t(9:22)

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Q

AML blood film

A

blast cells and Auer rods

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Q

Lymph node biopsy hodgkin lymphoma

A

Reed-sternburg cells

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Q

Reed sternburg cells are

A

abnormally large B cells that have multiple nuclei that have nucleoli

Q

CML Tx

A

Imatinib = tyrosine kinase inhibitor