L59 Flashcards

1
Q

What are the 3 organisms most likely to cause dermatophyte infection?

A
  1. Microsporum - WON’T cause tinea unguium
    - More common worldwide cause
  2. Epidermophyton - common cause of tinea cruris
  3. Trichophyton - most common US cause
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2
Q

What diseases are caused by dermaphytes?

A

Tinea + body part

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3
Q

What are the 2 types of tinea capitis?

A

Ectothrix - outside –> in destruction
- Does not damage hair bulb, hair will likely grow back
Endothrix - infection starts inside the hair bulb –> out

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4
Q

Which bug usually causes endothrix tinea capitis?

A

T.tonsurans = US

Microsporum world wide

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5
Q

What patients usually get tinea capitis?

A

Kids!

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6
Q

Treat tinea capitis

A
  1. Shampoo
  2. PO terbinafine
  3. Wash everything that could be contaminated!
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7
Q

What are the 3 types of tinea pedis?

A

Interdigital
Moccasin
Vesiculobullous

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8
Q

How do you get tinea corporis?

A

Direct body contact

  • To humans: wrestlers
  • To animals: horses
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9
Q

What is a tinea infection of the nails called?

A

Onychomycosis

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10
Q

How do you get/treat onychomycosis?

A

Can get independently or as a progression of other tinea infections (tinea pedis)
Treat with PO always! Need to penetrate the nail
- Terbinafine

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11
Q

If you’re using terbinafine as your first choice anti-fungal in most cases when you need a PO drug, what is your second choice?

A

Itraconazole

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12
Q

How do you treat most tineas (skin based infections)?

A

Topical: clotrimazole + miconazole

Add PO if severe

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13
Q

What bug causes tinea versicolor?

A

Malassezia furfur

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14
Q

What are the symptoms of tinea versicolor?

A

Hyper/hypopigmentation
Dandruff
Dermatitis
Folliculitis

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15
Q

If you scrape sample tinea versicolor, what do you see?

A

Spaghetti and meatballs

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16
Q

Treat tinea versicolor.

A

Shampoo + scrubbing

2. Terbinafine

17
Q

Dermophytes cause cutaneous mycoses. What is unique about this level of infection?

A

Will see inflammation b/c invading dermis - interacting with immune cells

18
Q

What do microsporum look like under the microscope?

A

Bottle nose!

19
Q

What are the 3 types of reservoirs for dematophyte infections?

A
Anthropophilic - humans
- Use us for our keratin!
- We fight off with cellular immunity 
Zoophilic - animals
Geophilic - soil
20
Q

Type of trichophyton that is most common cause of tinea pedis

A

T.rubrum

21
Q

Symptoms of tinea capitis

A

Papules
Nodules
Inflam = scaling, alopecia

22
Q

Define kerion

A

In tinea capitis - endothrix (T.tonsurans)
Result of cell mediated immune response
Severe inflam, hair loss, cervical lymphadenopathy

23
Q

How can you diagnose a dermatophyte?

A

KOH prep

Calcofluor prep