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HDID Block 2 > L55 > Flashcards

L55 Flashcards

1
Q

What bug causes syphilis?

A

Treponema pallidum

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2
Q

What are the 4 stages of disease for treponema pallidum?

A

Primary
Secondary
Tertiary
Congenital syphilis

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3
Q

Symptoms of 1ary syphilis

A

Chancre = painless ulcer on genitals

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4
Q

Symptoms of 2ary syphilis

A

“Flu”
Swollen lymph nodes
Spotted rash all over body (including palms & soles)

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5
Q

Symptoms of late syphilis

A

Chronic inflam + granulomatous lesions
CNS involvement = neurosyphilis
BV involvement = cardiovascular syphilis

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6
Q

How do you diagnose syphilis?

A

SEROLOGY
1st = RPR/VDRL
Follow up if + = FTA-ABS

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7
Q

What kind of serology test are RPR, VDRL? What info do these diagnostics give you?

A

Non-treponemal aka non-specific tests

Used to rule out syphilis - high FPs

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8
Q

What kind of serology test is FTA-ABS?

A

Treponemal = specific tests

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9
Q

Treat syphilis

A

Penicillin

Could use doxy

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10
Q

Treat neurosyphilis

A

Ceftriaxone

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11
Q

What bug causes Lyme disease

A

Borrelia burgdorferi

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12
Q

How would you stain for borrelia?

A

Giema stain (silver)

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13
Q

Lyme transmission

A

Ixodes ticks on deer or mice

Transmission requires prolonged feeding (24 hrs)

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14
Q

3 stages of Lyme disease

A

Early, localized
Early, disseminated
Late, disseminated

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15
Q

Symptoms of early, localized Lyme

A

Erythema migrans

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16
Q

Symptoms of early, disseminated Lyme

A

Timeframe = 3-5 wks post bite

  1. CN7 palsy (has forehead involvement) - 1 sided facial palsy
  2. Meningitis
  3. Cardiac dysfxn (reversible, heart block)
17
Q

Symptoms of late, disseminated Lyme

A

Arthritis

18
Q

Diagnose borrelia burgdorferi

A

If see erythema migrans - that’s enough!

Otherwise ELISA confirmed w/ Western blot

19
Q

Treat Lyme - 1st & 2nd choices

A

Doxy

2nd choice = ceftriaxone

20
Q

Which bug is transmitted in contaminated water via skin cuts?

A

Leptospira

Chronically infects kidneys of animals - pee bug into waters

21
Q

What are symptoms of Leptospirosis?

A

BIPHASIC

  1. Septicemic - acute, eye symptoms
  2. Immune - 1 mo after, liver + kidney failure
22
Q

Treat leptospirosis

A

Supportive

Penicillin or doxy

23
Q

What is the common drug that could work for spirochetes?

A

Doxy!!

HDID Block 2 (39 decks)

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