Foreign Body Infection

Question 1

What antimicrobial do you use for surgical prophylaxis?

Answer 1

Cefazolin

Question 2

What is the pre-septic state as dictated by unstable vitals?

Answer 2

SIRS

Question 3

What are the conditions of SIRS?

Answer 3

2+ of:
Temp 38
Pulse over 90
RR over 20
WBC over 12,000

Question 4

What is sepsis?

Answer 4

SIRS + suspected infection

Any infection, doesn’t have to bacterial

Question 5

If you’re trying to cover CAUTI, VAP, and line infections, what drugs do you start with before you get a definitive bug diagnosis?

Answer 5

Piperacillin/tazobactam + vanco

• Pip = pseudo coverage
• Vanco = MRSA coverage

Question 6

What drug classes cover pseudomonas?

Answer 6

1. Extended spectrum penicillin:
   - Pip/tazo
2. Cephalo
   - 3rd = Ceftazidime
   - 4th = Cefepime
3. Carbapenams
   - Meropenem
4. Fluoros
   - Cipro, moxi, levofloxacin
5. Aminoglycosides - gentamycin

Question 7

Name the 3 coag neg staph.

Answer 7

S. lugdenensis (native endocarditis)
S. saprophyticus (UTIs)
S. epidermidis

Question 8

Which GP bug are you thinking of for cocci in PAIRS?

Answer 8

Strep pneumo

Question 9

Which GP bugs are you thinking of for cocci in CHAINS?

Answer 9

Strep

Enterococci

Question 10

What do you do if you see staph aureus in the blood?

Answer 10

Always treat it

Question 11

What is your first line, broad drug to treat GP including MRSA?

Answer 11

Vanco

Question 12

Most common bug for arthroplasty?

Answer 12

S.epi

Question 13

What is the erythrocyte sedimentation rate?

Answer 13

Measure of inflammation - elevated indicates NON-specific inflam
Rate at which red blood cells sediment

Question 14

How do you treat prosthetic joint replacement w/ antimicrobials for staph epi?

Answer 14

Vanco - 6 wks

Linezolid - 3 wks

Question 15

What are negative side effects of linezolid?

Answer 15

Bone marrow suppression
Peripheral neuropathy
Lactic acidosis
Optic neuropathy