L33 Flashcards

1
Q

What is koch’s postulates

A

Guidelines used to demonstrate that a specific pathogen causes specific disease symptoms

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2
Q

What is the key stages of pathogenesis

A
  1. Adherence
  2. Invasion of host tissues
  3. Replication in host tissues
  4. Disease causing damage to host tissues
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3
Q

Adherence virulence factors

A

Use of fimbriae to bind to host

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4
Q

Invasion virulence factors

A

Motility (flagella)
Internalin related proteins

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5
Q

Replication virulence factors

A

Siderophores (Takes iron from surroundings)
Capsules (resist phagocytosis)

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6
Q

Disease virulence factors

A

Endotoxins: Cause inflammation
Exotoxins: Can be fatal

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7
Q

What are endotoxins

A

released when bacteria dies: Are Lipopolysaccharides which elicits strong immune reponse

Causes inflammation, fever, blood clot, shock

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8
Q

What are exotoxins and its 3 types

A

Produced in lliving bacteria then released into surrounding

Cytotoxins
Neurotoxins
Enterotoxins

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9
Q

What are cytotoxins

A

Lysis of red blood cells

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10
Q

What are neurotoxins

A

causes paralysis

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11
Q

Enderotoxins

A

Cause gastrointestinal damage

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