L3 - concept of medicine and dosage forms. Brands and generics Flashcards
how are medicinal products named (nomenclature)?
- brand name: given by pharma R&D company, registered name
- chemical name: name of the API, decided by an expert committee
why are some medicines’ shape and colour trademarked?
to identify and distinguish the goods of one manufacturer or seller from another, and to indicate the source
what are branded drugs?
new medicines marketed as a branded product
why do companies take out a patent on each new drug they discover?
to regain money spent on R&D and make a profit
patent vs marketing life
marketing life is the final stage of the patent
- used to gain profit and recover costs
what is the objective of pharmaceutical R&D?
to convert synthesised chemical compounds into candidate drugs for development
what does product development involve?
converting candidate drugs into dosage forms for registration and sale
what are NCEs?
new chemical entities
why do pharma companies need a pipeline of NCEs?
to gain market growth/shareholders and to fund the next gen of compounds
what is a blockbuster drug model?
where sales reach over US $1 bil per annum
what is the foundation of R&D strategy?
searching for a blockbuster
what are NMEs?
new molecular entities
what are BLAs?
biologics license applications
what are generic drugs?
a bioequivalent (PK and PD) to a leading brand name
what are the benefits of generic drugs?
- they cost less and are equally effective
- pharmacists have a wider choice of products to dispense
- important if there is a shortage of a particular product
