L49 - Liquid Dosage Forms: Suspensions And Emulsions

Question 1

What is acceptable suspensions?

Answer 1

• low rate of sedimentation
• disperse phase: easily redispersed with gentle shaking
• flow properties: formulatino easily removed from the container
• aesthetically pleasing

Question 2

What are advantages of pharmaceutical oral suspensions?

Answer 2

• delivery sys for low sol drugs
• avoid large vol of solvent (solution)
• avoid precipitation upon storage (cosolvent used)
• taste masking of drugs
• difficulty swallowing solid dosage forms
• controlled drug delivery

Question 3

What are disadvantages of pharmaceutical oral suspensions?

Answer 3

• problems - correct dose?
• unstable: formulation to ensure stability over period of shelf life
• aesthetic suspension: difficult
• bulky, difficult for patient to carry