L29 Digestion and Metabolism Flashcards

1
Q

what are the basic building blocks in the body?

A

nutrients

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2
Q

what are the 4 classes of nutrients?

A

essential and non essential amino acids, vitamins and minerals

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3
Q

what is vitamin B3?

A

a vitamin and a cofactor

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4
Q

what is iron?

A

a mineral and a cofactor

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5
Q

what is linoleic acid?

A

an essential amino acid

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6
Q

what is the GI tract?

A

gastrointestinal system = digestive system

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7
Q

what is the GI tract?

A

external way of interacting with enviornment in a nutritional/waste point of view

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8
Q

what does mucus consist of?

A

viscous water, amylase and glycoproteins

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9
Q

why can we not stop swallowing half way through?

A

it is a reflex - epiglottis prevents re-entry to mouth

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10
Q

what is coughing?

A

an involuntary reflex when swallowing reflex fails

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11
Q

what regulates movement in digestive system walls?

A

sphincters

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12
Q

what sphincter do we have voluntary control over?

A

anal sphincter

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13
Q

food is processed into a liquid called?

A

chyme

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14
Q

what is the pH of gastric juice?

A

2

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15
Q

what enzyme breaks protein bonds?

A

pepsin protease

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16
Q

where does HCl come from?

A

priorital cells secreted into stomach

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17
Q

where does HCl form?

A

lumen of stomach

18
Q

when does pepsin form?

A

in acidic conditions in presence of HCl

19
Q

what causes gastric ulcers?

A

bacteria called Heliobacter pylori

20
Q

where does most chemical digestion occur?

21
Q

how are fats partly digested?

A

bile salts

22
Q

what is life cycle of red blood cells?

A

120 days - bile kills them and recycles them via liver

23
Q

what does the hepatic artery do?

A

brings oxygen to liver, comes from GI tract and funnels nutrients to liver

24
Q

what is a lacteal?

A

part of lymphatic vessel that absorbs fat

25
what are chylomicrons?
a droplet of fat present in the blood or lymph after absorption from the small intestine
26
what minor role does appendix play?
immune response
27
where is faeces stored?
rectum
28
what regulates the digestive system/ GI tract?
endocrine and nervous system
29
what happens when we eat food?
medulla recieves a signal and autonomic nervous system causes secretion of saliva
30
conditioned reflex?
associating a certain stimulus with a certain response
31
what functions keep us alive?
vegetative functions - nutritional, metabolic, and endocrine functions
32
how is energy stored?
first in liver and then in glycogen, excess energy in adipose cells
33
when the body requires energy what occurs?
glycogen storage is used first followed by muscle glycogen and then fat stores
34
what is the absorptive state?
the body has been fed - glucose is plentiful - insulin regulates this state
35
what is the postabsorptive state?
this is fasting - energy stores are mobilised for energy, glucagon hormone is a major regulator
36
what is metabolic syndrome?
cluster of risk factors including insulin resistance, hypertension and high fat content
37
what is a central mechanism in insulin resistance?
chronic state of inflammation
38
what does obesity contribute to?
type 2 diabetes, cancer of colon and breat, heart attacks and strokes
39
how do hormones regulate appetite?
satiety centre in brain, ghrelin hormone triggers hunger
40
what secretes ghrelin?
stomach walls
41
what hormone suppresses appetite?
insulin and PYY - small intestine | Leptin - adipose tissue
42
what is an important concept in disease and health?
each individual has a unique microbiota/ bacterial fingerprint