L06 - Skeletal Muscle Pathophysiology Flashcards

1
Q

how does muscle respond to edurance and resistance training

what are the adaptations that can occur and examples

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2
Q

structural adaptation of muscles

what is the tot number of muscel fibres

what is hypertrophy in terms of muscles to a cellular level

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3
Q

what is the effect of endueance exercises

and non endurance exercises

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4
Q

how can ice and heat affect muscles and exercises. what used for

aspirin and msk pain.
why is it used. what is its mechanism. what is side effect

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5
Q

anabolic effects of testosterone??

what about steroid abuse? what are side effects

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6
Q

what is the effect of space flight on muscle

what about bed rest
how to treat

list different musc fibre types

bonus - what happens if limb is immpobilised for a lonh time???

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7
Q

what is a contracture for muscles and how does this happen

how do skeletal muscle cells develop and what is their dtructure after. how can you enlarge them

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8
Q

muscle regeneration

when does this. what is the cellular mechanism of this.

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9
Q

—–myalgia

what is it
CAUSES
what is it assoc with

——myopathy
what is it
what about dystrophies

what happens

——paresis

what is it

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10
Q

what is muscle pain
what is muscle weakness
what is weakness of vol movement
what is breakdown of skeletal muscle

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11
Q

what are the types of invol twitches

what is the difference

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12
Q

fasiculations and fibrilations?

what are they both

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13
Q

rhabdomyolysis

what is it
what does this have the risk of and why
what else

how to treat

what is it caused by

what are symptoms and signs

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14
Q

serum levels CPK - diagnostic

what is it. why is it measured. what can it imply if high

what is the clinical test

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15
Q

myoglobin - diagnostic

what does it do what is it

what does it indicate when its where

HYPERKALAEMIA
how is this related
also —– if incr or decr what does this mean

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16
Q

rigor mortis

why does this occur. when does it end

17
Q

myasthenia gravis

what is it and what is it caused by

why does it arise

what is its pathophysiology

what symptoms does it include

18
Q

what is progressive muscle weakness and fatigue. eye muscles

???

19
Q

treatment for MG

what can be given

A

ach inhib
neostigmine
edrophonium

immune
thymectomy
corticosteroids
plasmapheresis

20
Q

what could it be when a baby is floppy and has muscle weakness

21
Q

what is sma

what causes it - physiology and causes

22
Q

what is fibre type grouping

23
Q

what is it when someone gets very warm and ill when inhaling gas anaesthetics?

24
Q

malignant hyperthermia

what is it

what is it caused by and what happens

what is the result
symptoms??

what happens as a result

what can help it (medication)

25
what us a group of inherited disorders which cause severe and progressive muscle wasting known as?
muscular dysrophies
26
what are muscular dystrophies what is it due to (and not sure to) what are some symptoms what is an example of such a disease
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27
duchenne muscular dystrophy what is it how does it affect people what is it pathophysiology and cause
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