L06 - Skeletal Muscle Pathophysiology Flashcards

1
Q

how does muscle respond to edurance and resistance training

what are the adaptations that can occur and examples

A
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2
Q

structural adaptation of muscles

what is the tot number of muscel fibres

what is hypertrophy in terms of muscles to a cellular level

A
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3
Q

what is the effect of endueance exercises

and non endurance exercises

A
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4
Q

how can ice and heat affect muscles and exercises. what used for

aspirin and msk pain.
why is it used. what is its mechanism. what is side effect

A
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5
Q

anabolic effects of testosterone??

what about steroid abuse? what are side effects

A
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6
Q

what is the effect of space flight on muscle

what about bed rest
how to treat

list different musc fibre types

bonus - what happens if limb is immpobilised for a lonh time???

A

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7
Q

what is a contracture for muscles and how does this happen

how do skeletal muscle cells develop and what is their dtructure after. how can you enlarge them

A
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8
Q

muscle regeneration

when does this. what is the cellular mechanism of this.

A
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9
Q

—–myalgia

what is it
CAUSES
what is it assoc with

——myopathy
what is it
what about dystrophies

what happens

——paresis

what is it

A
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10
Q

what is muscle pain
what is muscle weakness
what is weakness of vol movement
what is breakdown of skeletal muscle

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11
Q

what are the types of invol twitches

what is the difference

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12
Q

fasiculations and fibrilations?

what are they both

A
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13
Q

rhabdomyolysis

what is it
what does this have the risk of and why
what else

how to treat

what is it caused by

what are symptoms and signs

A
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14
Q

serum levels CPK - diagnostic

what is it. why is it measured. what can it imply if high

what is the clinical test

A
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15
Q

myoglobin - diagnostic

what does it do what is it

what does it indicate when its where

HYPERKALAEMIA
how is this related
also —– if incr or decr what does this mean

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16
Q

rigor mortis

why does this occur. when does it end

A
17
Q

myasthenia gravis

what is it and what is it caused by

why does it arise

what is its pathophysiology

what symptoms does it include

A

nAChR

18
Q

what is progressive muscle weakness and fatigue. eye muscles

???

A

mg

19
Q

treatment for MG

what can be given

A

ach inhib
neostigmine
edrophonium

immune
thymectomy
corticosteroids
plasmapheresis

20
Q

what could it be when a baby is floppy and has muscle weakness

A

sma

21
Q

what is sma

what causes it - physiology and causes

A
22
Q

what is fibre type grouping

A
23
Q

what is it when someone gets very warm and ill when inhaling gas anaesthetics?

A
24
Q

malignant hyperthermia

what is it

what is it caused by and what happens

what is the result
symptoms??

what happens as a result

what can help it (medication)

A
25
Q

what us a group of inherited disorders which cause severe and progressive muscle wasting known as?

A

muscular dysrophies

26
Q

what are muscular dystrophies

what is it due to (and not sure to)

what are some symptoms

what is an example of such a disease

A
27
Q

duchenne muscular dystrophy

what is it
how does it affect people
what is it pathophysiology
and cause

A