Kinase Inhibitors Final Exam Flashcards
1
Q
Imantinib drug class
A
type II inhibitor of Abl-TK
2
Q
what should be tested prior to starting imantinib?
A
Abl gene
3
Q
ponatinib drug class
A
Bcr-Abl inhibitor
4
Q
what should be tested before starting ponatinib
A
Abl gene
5
Q
Midostaurin drug class
A
1st gen broad kinase inhibitor
6
Q
Midostaurin target
A
FTL3 mutation
7
Q
Quizartinib class
A
Type II kinase inhibitor
8
Q
Quizartinib target
A
ITD mutations
9
Q
Crenolanib class
A
2nd gen specific kinase inhibitor
10
Q
Crenolanib target
A
FTL3 mutations
11
Q
sirolimus drug class
A
rapamycin analog
12
Q
sirolimus target
A
inhibit mTOR
13
Q
Alectinib class
A
ALK inhibitor
14
Q
Dabrafenib class
A
BRAF v600 inhibitor
15
Q
trametinib class
A
MEK1 and MEK2 inhibitor
