Alkylators/Platinums Final Exam Flashcards by Madelynn Packer | Brainscape

Q

Chlorambucil class

A

alkylator

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Q

chlorambucil dose limiting

A

myelosuppression
secondary malignancies

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Q

chlorambucil DDIs

A

glutathione will decrease activity

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Q

what drugs are in the same class as chlorambucil

A

melphalan
bendamustine

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Q

cyclophosphamide class

A

alkylator

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Q

cyclophosphamide dose limiting effects

A

myelosuppression
secondary malignancies

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Q

cyclophosphamide DDIs

A

give with mesna to decrease bladder toxicity

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Q

mitomycin class

A

alkylator

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Q

mitomycin c dose limiting effects

A

myelosuppression

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Q

Cisplatin class

A

platinum

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Q

cisplatin cell cycle target

A

G1 more than s

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Q

cisplatin dose limiting side effect

A

nephrotoxicity

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Q

cisplatin DDI

A

glutathione will decrease activity

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