Key Area 6 Mutations And Key Area 7 Evolution Flashcards
What Is a mutation
It is a random and spontaous change in the genetic material
What causes mutation
Exposure to radiation
Exposure to chemical
What does a mutation result it
A protein not bring synthesised or a protien synthesis being altered
Types of mutations
Single genes mutation
Chromosomes
3 types of single gene mutations
Deletion
Insertion
Substitution
What is deletion with a single gene mutation
When a nucleotide is removed from a DNA strand
What is insertion in a single gene mutation
When a nucleotide Is added to the DNA strand
What is the result of the deletion on the single gene mutation
The strand is shorten
What I’d a result of a insertion in the single gene mutation
The strand is longer
Substitution in single gene mutation
When a nucleotide is swapped for another on the DNA strand
3 types of subsitions in single gene mutation
Missense
Nonsense
Splice-site
What is a missense mutation
Nucleotides being swapped for another leading a change of amino acids
What is a nonsense mutation
Results in a premature stop codon bring produced
What is a splice - site mutation
Sometimes are retained and/ or exons not included the mature mRNA transcription
What is the result of a missense mutation
Little effect or non functional protein
What is the result of a nonsense mutation
A shorter protien being synthesis
What is the result of splice- site mutation
May produce a non functional protien
What is a single gene mutation
It involves a chnage to one of the base pairs in the DNA sequence
What causes the frame shift mutation
Deletion and insertion
What is a chromosome structure mutation
They involve a change in the structure of one or more chromosomes
Types of chromosomes mutation
Deletion
Inversion
Translocation
Duplication
What is deletion for chromosomes mutation
This is when a section of chromosome is removed
What is inversion in chromosomes mutation
When a section of chromosomes is reversed
What is translocation in chromosomes
When a section of one chromosomes is added to another chromosomes that is not it’s homologus partner
What is duplication
Which a section of a chromosome is added from it’d homologus partner