Ipratropium Bromide Flashcards

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1
Q

What is the dose of ipratropium in acute severe asthma?

A

500microgram nebulised back to back with 5mg salbutamol

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2
Q

What is another indication for ipratropium?

A

COPD

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3
Q

What are the contraindications for ipratropium?

A

Hypersensitivity to ipratropium or atropine

Warnings: glaucoma, BPH, CF

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4
Q

Side effects of ipratropium

A

Headache, dizziness, dry mouth, blurred vision
Paradoxical bronchospasm (also salbutamol)
Urinary retention

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5
Q

Which drugs interact with ipratropium?

A

Additive effect with sympathomimetics and methylxanthines

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6
Q

How is ipratropium eliminated?

A

Active secretion into renal tubules

Half life 2-4 hours

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7
Q

How does ipratropium work?

A

Anticholinergic- blocks M3 muscarinic acetylcholine receptors, inhibiting parasympathetic bronchoconstriction

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