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Drugs- emergency and basic > Chlorphenamine > Flashcards

Chlorphenamine Flashcards

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Royal College: Emergency Medicine flashcards
1
Q

Dose of chlorphenamine in anaphylaxis

A

10mg IV

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2
Q

Contraindications of chlorphenamine

A

None in life threatening anaphylaxis

Relative: taken MAOi in last 14 days

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3
Q

Side effects of chlorphenamine

A

Drowsiness, anticholinergic effects

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4
Q

What interacts with chlorphenamine?

A

Metabolised by CYP450 so phenytoin etc

MAOi potentiates anticholinergic effects
Alcohol and hypnotics worsen drowsiness

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5
Q

How does chlorphenamine work?

A

Blocks histamine H1 receptors, stopping histamine release from mast cells

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Drugs- emergency and basic (21 decks)

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