Glucagon Flashcards
What are some alternate uses of glucagon
Decreasing intestinal motility for GI radiology
B or Ca blocker overdose which is refractory to fluids and inotropes (off licence)
When is glucagon indicated in hypoglycaemia
When the patient is unable to eat and there is no iv access
What is the dose of glucagon in hypoglycaemia?
1mg IM
What are the contraindications for glucagon?
Phaeochromocytoma, insulinoma
Side effects of glucagon
Nausea and VOMITING
Hypotension
Positive chronotropic and inotropic effect
Interactions of drugs with glucagon
Insulin - but don’t omit dose if due
Indomethacin makes glucagon less effective
Oral hypoglycaemics make the response to glucagon much slower
How does glucagon work?
Binds to receptors in the pancreas- stimulates gluconeogenesis, glycogenolysis to increase blood glucose levels