Ipratropium Bromide

Question 1

** Ipratropium Bromide**
Drug Class

Answer 1

Anticholinergic

Promotes bronchodilation by inhibiting cholinergic broncho motor tone

Question 2

** Ipratropium Bromide **
Onset

Answer 2

**NEB / MDI **
1.5 – 3 minutes

Question 3

Ipratropium Bromide
Duration

Answer 3

NEB/MDI
4 – 6 hours

Question 4

** Ipratropium Bromide **
Indications

Answer 4

Severe bronchospasm

Question 5

** Ipratropium Bromide**
Contraindications

Answer 5

Hypersensitivity to Ipratropium Bromide

Question 6

** Ipratropium Bromide **
Dose

Answer 6

Adult Nebulised
* 500 microg in 2 mL (250 microg/mL)
* dilute with 2-3ml NaCL 0.9%
* Repeat every 20 mins as required (total max dose 1.5mg)
Can be used concurrently with 5mg salbutamol in same nebuliser

Adult MDI
8 puffs (160 mcg), 1 breath per puff, where possible use spacer
Repeat MDI dose every 20 mins (total max 3 doses)

Paediatric Nebulised <6 yrs
* 250microg in1 mL
* Repeat every 20 mins as required (total max dose 750mcg)

Paediatric MDI less than 6 yrs
4puffs (80mcg), 1 breath per puff, where possible use spacer
Repeat MDI dose every 20 mins (total max 3 doses)

Paediatric Nebulised >6 yrs
* 500 microg in 2 mL (250 microg/mL)
* dilute with 2-3ml NaCL 0.9%
* Repeat every 20 mins as required (total max dose 1.5mg)

PaediatricMDI >6 yrs
8 puffs (160 mcg), 1 breath per puff, where possible use spacer
Repeat MDI dose every 20 mins (total max 3 doses)

Question 7

** Ipratropium Bromide**
Side Effects

Answer 7

Dilated Pupils
Dry mouth
Palpitations