Atropine

Question 1

Atropine
Drug Class

Answer 1

Anti cholinergic Agent:

Inhibits the parasympathetic nervous system allowing an unchallenged sympathetic response.

Question 2

** Atropine**
Onset

Answer 2

1-2 mins (peak 15-50 mins)

Question 3

** Atropine**
Duration

Answer 3

Up to 5 hours

Question 4

** Atropine**
Indications

Answer 4

*** Symptomatic Bradycardia **
* Hypotension
* Altered conscious state
* Diaphoresis
* Shortness of breath
* Cyanosis
* Syncope
* Pale skin

* Organophosphate poisoning

Question 5

** Atropine**
Contraindications

Answer 5

• Known hypersensitivity to Atropine
• Patients with cardiac transplant

Question 6

** Atropine **
Preparation

Answer 6

Symptomatic Bradycardia - Un diluted

Organophosphate Poisoning - Dilute 1.2 mg/1 mL with 11 mL saline for 1.2 mg/12 mL (100 microg/mL)

Question 7

**Atropine **
Symptomatic Bradycardia
Dose

Answer 7

Adult - IV/IO 0.6 mg in 0.5 mL every 3-5 minutes (Total max dose 3 mg)

Paediatric - ASMA Consult required

Question 8

Atropine
organophosphate poisoning
Dose

Answer 8

Adult - IV/IO, 1-2 mg (10-20 mL)
Repeat every 5 minutes until atropinisation

Paediatric - IV/IO, 0.02 mg/kg
repeat every 5 minutes until atropinisation

Question 9

** Atropine**
Side effects

Answer 9

• Agitation
• Hallucinations
• Dilated Pupils
• Dry mouth/dry skin/reduced bronchial secretions
• Tachycardia